Sökning: "malignant melanoma"

Visar resultat 16 - 20 av 155 avhandlingar innehållade orden malignant melanoma.

  1. 16. Wnt5a signaling in Malignant Melanoma

    Författare :Elin Ekström; Malmö Experimentell patologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : The Wnt signaling pathway is highly conserved and crucial during embryonic development. Aberrant Wnt signaling is important in several different disease processes. One such disease process is the development and progression of cancer. Malignant melanoma is a highly aggressive tumor type, in which Wnt signaling is essential. LÄS MER

  3. 17. Immunological Studies in Malignant Melanoma : Importance of TNF and the Thioredoxin System

    Författare :Anna-Maria Barral; Anders Rosén; R. Kiessling; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Malignant melanoma is a tumor whose incidence is dramatically increasing in persons with light-coloured skin in all parts of the world. Due to its resistance against traditional chemo- and radiotherapy, melanoma has been a favourite target of alternative therapies, in particular those involving immunological mechanisms. LÄS MER

  4. 18. Cutaneous malignant melanoma : body site, sun exposure, genetic factors and prognosis

    Författare :Daniela Gordon; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Melanoma;

    Sammanfattning : Background: The interplay between tumor site, ultraviolet radiation (UVR) exposure, genetic factors and various epidemiological parameters of cutaneous melanoma is complex. In this thesis, we aimed to investigate the impact of detailed body site of the primary tumor beyond the conventional and strictly anatomic division of the head-neck, trunk, upper- and lower extremities, focusing on body site division according to UVR exposure patterns in relation to risk, outcome and other factors. LÄS MER

  5. 19. Cutaneous malignant melanoma : aspects on prevention

    Författare :Mia Bergenmar; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Melanoma; Early detection; Prevention; Information; Dysplastic Nevus Syndrome; Knowledge; UV-exposure;

    Sammanfattning : The general aims of the present thesis were to delineate factors of importance for prevention of cutaneous malignant melanoma (CMM). Three samples of patients with CMM, one sample of patients with dysplastic nevus syndrome (DNS) and a sample from the general population were studied. LÄS MER

  7. 20. Malignant melanoma in children and adolescents

    Författare :Peter Berg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Melanoma; epidemiology; cancer register; children; adolescents; incidence; phototherapy; hyperbilirubinaemia; etiological factors; congenital nevi; heredity; CDKN2A; germline mutation.;

    Sammanfattning : The aim of the work reported in the present thesis was to investigate malignant melanoma in children and adolescents. Through epidemiological studies, we wished to investigate incidence, clinical factors and prognosis and to study the records. LÄS MER