Sökning: "malignancy"

Visar resultat 26 - 30 av 402 avhandlingar innehållade ordet malignancy.

  1. 26. Anti-TNF therapy and malignancy in patients with rheumatoid arthritis : studies on cancer incidence, recurrence and survival

    Författare :Pauline Raaschou; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Tumor necrosis factor i nhibitors (TNFi) h ave become a backbone treatment of rheumatoid arthritis (RA). TNF has multiple and incompletely understood functions in tumor biology, and cancer is considered a potential adverse event of TNFi treatment. LÄS MER

  3. 27. A histopathologic malignancy grading system for indication of prognosis in invasive squamous cell carcinoma of the uterine cervix

    Författare :Ulf Stendahl; Uppsala universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : .... LÄS MER

  4. 28. Effects of interferon on cellular proliferation and apoptosis

    Författare :Olle Sangfelt; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :interferon; malignancy; apoptosis; cell cycle;

    Sammanfattning : Interferon (IFN) therapy is today a well-established treatment in many diseases, including various malignancies. How IFN exerts antitumor activity is not known, but several mechanisms have been suggested. LÄS MER

  5. 29. Telomerase activity and its regulation in malignant hematopoietic cells

    Författare :Dawei Xu; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :hTERT mortalization malignancy activity telomerase regulation;

    Sammanfattning : Telomerase, a multicomponent ribonucleoprotein, synthesizes TTAGGG telomeric repeats essential for the stability and integrity of chromosomes. Most normal human somatic cells exhibit undetectable telomerase activity. LÄS MER

  7. 30. The risk of second primary lung carcinoma in breast cancer patients

    Författare :Michaela Prochazka; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Breast cancer; second primary malignancy; lung cancer; radiotherapy; smoking; validation study; familial risk;

    Sammanfattning : The overall aim of this thesis was to investigate the risk of second primary malignancies - with a special focus on lung cancer - in a cohort of approximately 152,000 Swedish women diagnosed with breast cancer between 1958 and 2000. With recent advances in early diagnosis and treatment, breast cancer is becoming an increasingly survivable disease. LÄS MER