Sökning: "malignancies"

Visar resultat 11 - 15 av 492 avhandlingar innehållade ordet malignancies.

1. 11. Infections in patients with haematological malignancies

   Författare :Honar Cherif; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Haematological malignancies; febrile neutropenia; bacteraemia; Candida; oral antibiotic; risk stratification; FUO; cefepime; splenectomy; pneumococcal vaccine;

   Sammanfattning : Infectious complications are an important cause of morbidity and mortality in patients with hematological diseases, especially during chemotherapy induced neutropenia. This study was undertaken with the ultimate goal to improve the clinical management of infections in patients with hematological diseases. LÄS MER

3. 12. Hemophagocytic lymphohistiocytosis and associations with malignancies

   Författare :Alexandra Haara Löfstedt; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : In immune homeostasis, natural killer cells and cytotoxic T cells are responsible for clearance of virus-infected and tumor transformed cells, but also for turning off the immune response. Patients with familial hemophagocytic lymphohistiocytosis (HLH) have impaired cytotoxic function due to genetic aberrations in genes in the perforindependent cytotoxic pathway. LÄS MER

4. 13. B lymphocytes in solid human malignancies

   Författare :Ali Zirakzadeh; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Cancer remains one of the leading causes of death worldwide. Modern treatments such as immunotherapy and neoadjuvant chemotherapy exhibit promising results. However better understanding of the treatments may lead to optimizations and consequently better prognosis. LÄS MER

5. 14. Sexuality in patients treated for hematologic malignancies - Problems and need for support from patients’ and nurses’ perspectives

   Författare :Cecilia Olsson; Maria Larsson; Ann-Kristin Sandin-Bojö; Kaisa Bjuresäter; Karin Ahlberg; Karlstads universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cancer patients; hematologic malignancies; nursing; nurse-patient communication; support; sexuality; body image; health related quality of life; Nursing Science; Omvårdnad;

   Sammanfattning : Aim: The overall aim of this thesis was to describe and explore how sexuality, body image and HRQoL were affected in patients treated for hematologic malignancies, and their need for support. A further aim was to describe nurses’ conceptions of dialogues about sexuality. LÄS MER

7. 15. Clinical impact of epoetins in the treatment of anemia with special emphasis on patients with lymphoid malignancies. : dosing, iron supplementation and safety

   Författare :Michael Hedenus; Jack Lindh; Anders Österborg; Robert Hast; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; anemia; cancer; lymphoproliferative malignancies; erythropoietin; intravenous iron; safety; Oncology; Onkologi; Oncology; onkologi;

   Sammanfattning : The aim of this thesis was to determine the relevant dose of arbepoetin-alfa (DA) in patients with lymphoproliferative diseases (LPD) and chemotherapy induced anemia (CIA), to study the clinical impact of intravenous (IV) iron supplementation combined with epoetin beta treatment, to identify factors that might predict hemoglobin (Hb) response to treatment with epoetins and to investigate safety of DA.A dose-finding phase II study was able to assess a reasonable DA dose of 2. LÄS MER