Sökning: "male mutation bias"
Visar resultat 1 - 5 av 9 avhandlingar innehållade orden male mutation bias.
1. Mutation and Diversity in Avian Sex Chromosomes
Sammanfattning : Sex chromosomes are useful for the study of how factors such as mutation, selection, recombination and effective population size affect diversity and divergence.A comparison of gametologous introns in seven different bird species revealed a complete lack of diversity on the female-specific W chromosome. LÄS MER
2. The Effects of Mutation and Selection on the Rate and Pattern of Molecular Evolution in Birds
Sammanfattning : By comparing sequence diversity and divergence on sex chromosomes one can study how the rate of evolution in affected by mutation and/or selection. The rate of mutation in male biased, meaning that relatively more mutations are created in the male germ line than in the female. LÄS MER
3. Genomic studies of sex differences : On mutations, recombination, and sexual antagonism in songbirds
Sammanfattning : Many organisms have separate sexes, i.e., males and females. The presence of separate sexes causes sex-specific selection regimes and sexual antagonism, which can lead to sex differences in morphology, physiology, and behaviours. LÄS MER
4. Prostate cancer : epidemiological studies of risk factors
Sammanfattning : In spite of the fact that prostate cancer is the most common male cancer in both Sweden and many other countries in the developed world, little is known of risk factors and predisposing conditions. The only well recognized risk factors are age, race and familial aggregation. LÄS MER
5. Molecular studies on Hirschsprung disease and 'Ondine's curse'
Sammanfattning : This thesis is based on molecular studies of two diseases that arise from dysfunction of, defective migration or inappropriate apoptosis of neural crest derived cells: Hirschsprung disease (HSCR) and "Ondine's curse" (congenital central hypoventilation syndrome, CCHS). The neural crest (NC) is a condensation of pluripotent cells of ectodermal origin. LÄS MER