Sökning: "malaria"

Visar resultat 6 - 10 av 278 avhandlingar innehållade ordet malaria.

  1. 6. Polyamine Pathway as Drug Target against Malaria

    Författare :Janina Sprenger; Biogena aminer; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Amino acid insertions; Crystallography; polyamine pathway; drug design; enzyme inhibition; ITC; ligand binding; malaria; Plasmodium falciparum; S-Adenosylmethionine decarboxylase; spermidine synthase.;

    Sammanfattning : Malaria, caused by the protozoan parasite Plasmodium falciparum is responsible for about 600.000 death cases every year. Mainly affected are populations of subtropical countries in Africa and the largest groups of victims are children below the age of 5 years. LÄS MER

  3. 7. Host responses to malaria and bacterial co-­infections

    Författare :Maria Nelson; Johan Normark; Sven Bergström; Anna Fahlgren; Olle Stendahl; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Plasmodium; Malaria; Borrelia; S. pneumoniae; Co-infection; Immunology; Metabolomics;

    Sammanfattning : The two main causes of child mortality and morbidity in Africa are malaria and invasive bacterial diseases. In addition, co-infections in sub-Saharan Africa are the rule rather than the exception. However, not much is known about the host-pathogen interaction during a concomitant infection or how it affects the outcome of disease. LÄS MER

  4. 8. Studies on malaria blood stage infection and host responses

    Författare :Lili Xu; Klavs Berzins; Adrian Luty; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Malaria; cytokines; parasite ligands; merozoite released soluble proteins MRSPs ; molekylär biovetenskap; Molecular Biosciences;

    Sammanfattning : The challenges in controlling malaria infectious disease are increasing due to drug resistance and incomplete immunity induced by malaria infection. Moreover there is no effective vaccine available against malaria blood stage infection. LÄS MER

  5. 9. Relation of nutritional status, immunity, hemoglobinopathy and falciparum malaria infection

    Författare :Alice Nyakeriga; Marita Troye-Blomberg; Thomas Williams; Clara Menendez; Stockholms universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Iron deficiency; nutrition; anthropometric indexes; malaria; hemoglobinopathies; immunity; Immunology; Immunologi;

    Sammanfattning : The interaction between nutritional status and malaria disease is complex and often controversial. Nutritional deficiencies (macro- or micro-nutrient) are thought to lead to malnutrition with subsequent susceptibility to malaria infection. On the other hand severe malaria or repeated malaria infections lead to malnutrition. LÄS MER

  7. 10. Towards Climate Based Early Warning and Response Systems for Malaria

    Författare :Maquins Odhiambo Sewe; Joacim Rocklöv; Clas Ahlm; Yesim Tozan; Madeleine Thomson; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Malaria; Mosquito; Lead time; Early Warnings; Forecasts; Economic Evaluation; Rainfall; KEMRI CDC HDSS; Kenya; Temperature; LST; NDVI; Climate; HDSS; GAM; GAMBOOST; DLNM; Remote Sensing; Net Benefit; Cost-Effectiveness; Boosting Regression; Weather; Public Health; Infectious Diseases; folkhälsa; Public health; Epidemiology; epidemiologi;

    Sammanfattning : Background: Great strides have been made in combating malaria, however, the indicators in sub Saharan Africa still do not show promise for elimination in the near future as malaria infections still result in high morbidity and mortality among children. The abundance of the malaria-transmitting mosquito vectors in these regions are driven by climate suitability. LÄS MER