Sökning: "major depressive disorder"

Visar resultat 11 - 15 av 72 avhandlingar innehållade orden major depressive disorder.

1. 11. Bipolar disorder in rural Ethiopia : community-based studies in Butajira for screening, epidemiology, follow-up, and the burden of care

   Författare :Alemayehu Negash; Jayanti Chotai; Hans Ågren; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Butajira; bipolar 1 disorder; screening; epidemiology; neurological soft signs; burden of care; Psychiatry; Psykiatri; psykiatri; Psychiatry;

   Sammanfattning : Background: The challenges of research in economically stunted countries’ settings remains a profound concern and is linked to socioeconomic development of these countries. More research is needed regarding psychiatric morbidity in rural areas of the developing and poverty stricken countries. LÄS MER

3. 12. On the efficacy and prescription of serotonin reuptake inhibitors

   Författare :Alexander Lisinski; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; antidepressants; antidepressive agents; major depressive disorder; selective serotonin reuptake inhibitor; serotonin and noradrenaline reuptake inhibitor; tricyclic antidepressant;

   Sammanfattning : This thesis addresses several controversial issues regarding commonly used antidepressants, including selective serotonin reuptake inhibitors (SSRIs), serotonin and noradrenaline reuptake inhibitors (SNRIs), and tricyclic antidepressants (TCAs). To this end, patient-level data from 28 placebo-controlled trials on SSRIs and 13 corresponding trials on the SNRI duloxetine, were requested and obtained. LÄS MER

4. 13. In vivo and in vitro studies of the serotonin 1B receptor in relation to major depressive disorder and treatment with ketamine

   Författare :Emma R Veldman; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Despite the large implications of Major Depressive Disorder (MDD) on disease burden worldwide, current treatment options are suboptimal and a third of patients suffering from this disease do not respond to treatment. Therefore, an unmet need exists for the development of new treatment options and methods to aid appropriate treatment selection in individual patients. LÄS MER

5. 14. Recovery from dysthymia and panic disorder : options and obstacles

   Författare :Cecilia Svanborg; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Dysthymic disorder; panic disorder; personality disorder; remission; recovery; mixed methods design; long-term follow-up; therapeutic relationship; patient preferences and experiences;

   Sammanfattning : Dysthymia, a depressive disorder with usually an insidious, early onset (before age 21), and panic disorder are psychiatric disorders with a major impact on public health due to their high frequency of recurrence, persistent course and superimposed major depressions. This thesis aimed to improve knowledge of factors that help or hinder recovery from such disorders in ordinary outpatient psychiatric settings. LÄS MER

7. 15. Mitochondrial dysfunction and alterations of brain HMPAO SPECT in depressive disorder : perspectives on origins of 'somatization'

   Författare :Ann Gardner; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :99mTc-d; 1-hexamethylpropyleneamine oxime; clinical rating scales; hearing loss; mtDNA; muscle biopsy; PCR; single photon emission computed tomography; tinnitus; unipolar depression.;

   Sammanfattning : A range of somatic symptoms are more common in patients with major depression than in the general population. Similar somatic symptoms and depression have been described in mitochondrial disorders, in which decreased production of adenosine triphosphate (ATP) is found. LÄS MER