Sökning: "magnus grenegård"

Visar resultat 1 - 5 av 11 avhandlingar innehållade orden magnus grenegård.

  1. 1. Platelets : intracellular signalling and cellular interaction

    Författare :Magnus Grenegård; Hans Gyllenhammar; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Activation of platelets is essential to prevent excessive blood loss at the site of vascular injury. These highly reactive cell fragments are also involved in several pathological conditions, in particular arterial thrombosis, which, in the coronary vessels, can lead to reduced blood flow, vessel occlusion and myocardial infarction. LÄS MER

  3. 2. Analysis of new biomarkers and their kinetics in connection with ST-elevation myocardial infarction and percutaneous coronary intervention

    Författare :Rahel Befekadu Wodajo; Sofia Ramström; Magnus Grenegård; Anders Larsson; Dick Wågsäter; Örebro universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; STEMI; PTX3; sTNFR1; sTNFR2; Cathepsin S; MASP-1 AT MASP-1 C1-INH; MASP-2 AT; MASP-2 C1-INH;

    Sammanfattning : This thesis studies different biomarkers in a cohort of patients suffering from ST-elevation myocardial infarction (STEMI) who underwent Percutaneous coronary intervention (PCI) in Örebro in 2011-2012. Blood samples were collected at three time points, at the arrival at the hospital, 1-3 days after PCI and for a smaller group of patients also 3 months after PCI. LÄS MER

  4. 3. α1-acid glycoprotein modulates the function of human neutrophils and platelets

    Författare :Peter Gunnarsson; Magnus Grenegård; Henrik Thorlacius; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : The acute-phase protein α1-acid glycoprotein (AGP; orosomucoid) was initially identified andcharacterised in the 1950s. The normal plasma concentration is around 0.5-1 mg/ml butduring inflammation the concentration increase several fold and the carbohydrate compositionof the protein changes. LÄS MER

  5. 4. Studies of platelet signalling and endothelial cell responses using unique synthetic drugs

    Författare :Caroline Kardeby; Magnus Grenegård; Knut Fälker; Liza Ljungberg; Alastair W. Poole; Örebro universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Haemostasis; glycopolymers; purine analogue; PEAR1; GPIbα; CLEC-2; inflammation; ROCK;

    Sammanfattning : Haemostasis is a complex and tightly regulated process which protects us from bleeding. Platelets are essential for maintained haemostasis. Under normal conditions platelets are calmed by antithrombotic substances release by the endothelium. During vascular injury, the platelets will activate and form a haemostatic plug to prevent bleeding. LÄS MER

  7. 5. Differentiation of Human Dermal Fibroblasts : a New Tool in Vascular Tissue Engineering

    Författare :Lisa Karlsson; Gunnar Kratz; Magnus Grenegård; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Tissue engineering is an expanding field, which focuses on the development of func-tional substitutes for damaged tissues. A limitation in this field is difficulties with obtaining autologous cells. Recent research has shown the presence of cells with multilineage-potential within the connective stroma of the skin. LÄS MER