Sökning: "macrovascular"

Visar resultat 1 - 5 av 30 avhandlingar innehållade ordet macrovascular.

  1. 1. A Longitudinal Study of Diabetes Mellitus : With Special Reference to Incidence and Prevalence, and to Determinants of Macrovascular Complications and Mortality

    Författare :Stefan P.O. Jansson; Dan K.G. Andersson; Kurt Svärdsudd; Mats Eliasson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Diabetes mellitus; clinical epidemiology; longitudinal study; prevalence; incidence; mortality; macrovascular complications; pharmacological diabetes treatment; hypertension treatment; screening; Family Medicine; Allmänmedicin;

    Sammanfattning : Objectives. To investigate diabetes prevalence, incidence, mortality trends, the effects of hyperglycaemia and blood pressure, diabetes and hypertension treatment, and the effect of screening detection on total and cardiovascular disease (CVD), myocardial infarction (MI) and stroke incidence.Study population and methods. LÄS MER

  3. 2. On macrovascular and renal complications in type 1 diabetes : aspects on glycemic memory

    Författare :Björn Rathsman; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : There is a substantially increased risk of premature mortality and morbidity in cardiovascular disease (CVD) among type 1 diabetes individuals compared to individuals without diabetes. Development of microangiopathy and markers of macrovascular complications precedes these events. LÄS MER

  4. 3. Expression and function of IGF-I and insulin receptors in human micro- and macrovascular cells

    Författare :Simona I. Chisalita; Hans J. Arnqvist; Torbjorn Lindström; Per-Anders Jansson; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Insulin-like growth factor and insulin are phylogenetically closely related polypeptides and have large structural and biological similarities. Low circulating insulin-like growth factor-I (IGF-I), diabetes as well as insulin resistance have been implicated in the pathogenesis of cardiovascular disease, but the mechanisms involved are still not clear. LÄS MER

  5. 4. Genetics of complications in patients with type 2 diabetes

    Författare :Sami Alkayyali; diabetes och endokrinologi Genomik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; genetics; genome-wide association studies; type 2 diabetes; diabetes complications.;

    Sammanfattning : Type 2 diabetes (T2D) is a polygenic disease caused by an interaction between genetic and environmental factors such as low physical activity, smoking, and obesity. The disease is associated with devastating chronic microvascular (nephropathy, retinopathy, and neuropathy) and macrovascular (coronary heart disease and stroke) complications. LÄS MER

  7. 5. Cardiovascular role of PDGF-B in development and disease. Studies in genetically engineered mice

    Författare :Henrik Nyström; Göteborgs universitet; []
    Nyckelord :atherosclerosis; cardiovascular disease; cell retention; in vivo physiology; neointimal hyperplasia; PDGF; transgenic mice; vascular function; vascular smooth muscle cell;

    Sammanfattning : Platelet-derived growth factor B (PDGF-B) is vital for microvascular development, and retention of PDGF-B to extracellular matrix (ECM) is important in this process. However, the role and source of PDGF-B in development of macrovascular function is disputed. LÄS MER