Sökning: "macrophages"
Visar resultat 6 - 10 av 742 avhandlingar innehållade ordet macrophages.
6. Molecular targets for glucocorticoids in macrophages: cytosolic phospholipase A2 and cytokine formation
Sammanfattning : The aim of this investigation has been to study mechanisms by which glucocorticoids inhibit inflammatory processes in vitro. Type IV cytosolic 85 kDa phospholipase A2 (cPLA2) is an important modulator of inflammatory responses that is present in macrophages as well as in other cell types. LÄS MER
7. Signalling to Activation of Cytosolic Phospholipase A2 and Arachidonate Release in Macrophages
Sammanfattning : Eicosanoids include prostaglandins, thromboxanes and leukotrienes, which are arachidonic acid oxygenation products. These lipids make important contributions to the signs and symptoms of inflammatory diseases. LÄS MER
8. Macrophages, Nitric oxide synthases and Heme oxygenases: possible roles during peripheral nerve regeneration
Sammanfattning : The purpose of this study was to investigate the suggestions that macrophages, and the systems generating nitric oxide (NO) and carbon monoxide (CO), i.e. nitric oxide synthases (NOS) and heme oxygenases (HO), could be important for peripheral nerve regeneration. LÄS MER
9. On macrophage contributions to tissue homeostasis : New insights on pancreas development and healing of ischemic injury
Sammanfattning : Besides providing host defence against innumerable threats, macrophages display additional key functions for preservation of tissue homeostasis. This thesis includes four studies that explore novel macrophage functions in both the development of islets of Langerhans and healing of ischemic injury in mice. LÄS MER
10. Macrophage programming and host responses to bacterial infection
Sammanfattning : Macrophages are dynamic, plastic, and heterogeneous immune cells that play an important role in host immune defense against bacterial infection. Various bacterial pathogens, such as Neisseria meningitidis and Mycobacterium tuberculosis, can modulate host immune responses by interfering with macrophage differentiation and polarization. LÄS MER