Sökning: "macrophage tropism"
Hittade 3 avhandlingar innehållade orden macrophage tropism.
1. Virus tropism and neutralization response in SIV infection
Sammanfattning : Simian immunodeficiency virus (SIV) infections in macaques are commonly used as models to study the pathogenesis of human immunodeficiency virus (HIV). Both SIV and HIV normally use the CD4 receptor and an additional coreceptor for cell entry. The most common coreceptors used by HIV are CCR5 and CXCR4. LÄS MER
2. Biological determinants of HIV infection : studies of viral evolution during disease progression in children and adults
Sammanfattning : Coreceptor usage of primary HIV-1 isolates was analysed in relation to their biological phenotype and the severity of HIV-1 infection in the patient. The indicator cell lines, U87 glioma cells engineered to express CD4 and one of the chemokine receptors CCR1, CCR2b, CCR3, CCR5 or CXCR4, were infected with a panel of well-characterized primary HIV-1 isolates. LÄS MER
3. Phenotype and function of intestinal CD103+ dendritic cells
Sammanfattning : Mucosal tissues such as the intestine present an enormous surface area to the outside environment and are continually exposed to foreign antigens in food and microflora. Thus, the intestinal mucosa must must remain tolerant to these innocuous antigens while at same time be able to mount effective immune responses to pathogens. LÄS MER