Sökning: "macroangiopathy"

Hittade 4 avhandlingar innehållade ordet macroangiopathy.

  1. 1. Early arterial disease of the lower extremities in diabetes : diagnostic evaluation and risk markers

    Författare :David Sahli; Maria Svensson; Eric Wahlberg; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; diabetes mellitus; ankle blood pressure; toe blood pressure; screening; risk markers; mediasclerosis; macroangiopathy; fibrinolysis; inflammation; MEDICINE; MEDICIN; Diabetology; Diabetologi;

    Sammanfattning : The aim of the present thesis was to assess the occurrence of early lower extremity arterial disease (LEAD) in patients with diabetes and to assess novel potential risk markers for development or worsening of LEAD in the same patients. In parallel different measures of impaired peripheral circulation were evaluated. LÄS MER

  3. 2. IGF-I receptors, insulin receptors and insulin/IGF-I hybrid receptors in human endothelial cells : with special reference to diabetes

    Författare :Marloes Dekker Nitert; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Patients with diabetes mellitus are known to develop vascular complications, which occur as macroangiopathy, atherosclerosis and mediasclerosis, as well as microangiopathy, e.g. retinopathy and nephropathy. The precise mechanisms causing these complications have not yet been elucidated. LÄS MER

  4. 3. Role of GLP-1 receptor agonists in endothelial function

    Författare :Özlem Erdogdu; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Type 2 diabetes;

    Sammanfattning : BACKGROUND: The leading cause of death for patients suffering from type 2 diabetes is macrovascular disease. Endothelial dysfunction is one of the earliest events identified in the pathogenesis of atherosclerosis. Hence, there is a need for finding glucose-lowering agents that cause direct positive effects on vasculature in diabetic patients. LÄS MER

  5. 4. On endothelial function in type 2 diabetic patients with coronary artery disease

    Författare :Thomas Nyström; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Type 2 diabetes; endothelial dysfunction; insulin resistance; coronary artery disease; nitric oxide; glucagon-like peptide 1; exendin; tetrahydrobiopterin; inflammation; adiponectin; resistin; C-reactive protein; tumor necrosis factor a; interleukin-6;

    Sammanfattning : Patients with type 2 diabetes have a poor outcome suffering a myocardial infarction (MI). Endothelial dysfunction may play a role in this poor prognosis. In type 2 diabetes, endothelial dysfunction is a salient feature coexisting with obesity and insulin resistance and may be linked by the same pathophysiology, i.e. LÄS MER