Sökning: "lysine"

Visar resultat 1 - 5 av 150 avhandlingar innehållade ordet lysine.

1. 1. Therapy with 177Lu-octreotate - pharmacokinetics, dosimetry and kidney toxicity

   Författare :Maria Larsson; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; PRRT; 177Lu-octreotate; 111In-octreotide; dosimetry; biokinetics; scintigraphy; conjugate view method; renal function; renal toxicity; lysine; DMSA; 99mTc-DTPA; 99mTc-DMSA;

   Sammanfattning : 177Lu-octreotate is used for treatment of patients with somatostatin receptor expressing neuroendocrine tumors in some clinics using a standard schedule. Renal and bone marrow toxicity are the main limiting factors. LÄS MER

3. 2. Cell-Penetrating Penetratin Peptides - Mechanistic Studies on Uptake Pathways and DNA Delivery Efficiency

   Författare :Helene Åmand; Chalmers tekniska högskola; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Plasma membrane vesicle; Lysine; Stimulated endocytosis; Gene delivery; Cell surface affinity; Penetratin; Cell-penetrating peptide; Cysteine; Uptake; Arginine;

   Sammanfattning : Delivery of gene-targeted drugs is limited by the inherently poor capacity of nucleic acids to overcome the membrane barrier of the cell, and development of vectors that can promote uptake is therefore crucial. Cell penetrating peptides (CPPs) have emerged as promising vector candidates due to their ability to deliver a wide range of macromolecular cargos into cells. LÄS MER

4. 3. Structure and distribution of alpha-1-microglobulin proteins

   Författare :Tord Berggård; Institutionen för experimentell medicinsk vetenskap; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Proteins; lysine; chromophore; placenta; immunohistochemistry; albumin; prothrombin; plasma; bikunin; lipocalin; alpha-1-microglobulin; protein HC; enzymology; Proteiner; enzymologi;

   Sammanfattning : This thesis describes studies of the structure and tissue distribution of alpha-1-microglobulin (a1-m), a member of the lipocalin protein superfamily with immunosuppressive properies. It was shown that a1-m appears in human plasma in five major forms. LÄS MER

5. 4. POLYPEPTIDES - STRUCTURES AND INTERACTIONS IN MONOLAYERS AND AQUEOUS SOLUTIONS

   Författare :Helen Sjögren; Fysikalisk kemi; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Physical chemistry; Fysikalisk kemi; tyrosine ; co-poly-L lysine; phenylalanine ; co-poly-L- lysine; poly-L-glutamate; poly-L-lysine; poly-L-valine; poly-L-isoleucine; poly-gamma-methyl-L-glutamate; poly-L-leucine; monolayer; Langmuir-Blodgett film; CD spectroscopy; random coil; alpha-helix; surfactant stabilisation; polypeptide; polyamino acid;

   Sammanfattning : The aim of this thesis work is to understand and be able to control polypeptide conformation and interactions at interfaces and in solution by changing the solution conditions. For this purpose simple model polypeptides, so-called polyamino acids, have been investigated at the air-liquid interface, as well as in aqueous solutions. LÄS MER

7. 5. Engineering synthetic pathways for adipic acid biosynthesis

   Författare :Jae Ho Shin; Chalmers tekniska högskola; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; metabolic engineering; cell factory; Corynebacterium glutamicum; L-lysine; GC MS; lignocellulose; adipic acid; benzoic acid; pathway engineering; muconic acid; cultivation; analytical chemistry; in silico docking;

   Sammanfattning : Utilization of petroleum in consumer product manufacturing is causing irreversible environmental damage. Its impact on land, sea, and air calls for the development of more sustainable technologies based on the use of renewable materials such as lignocellulosic biomass and its conversion into platform chemicals. LÄS MER