Sökning: "lyophilization"

Visar resultat 1 - 5 av 6 avhandlingar innehållade ordet lyophilization.

  1. 1. Theoretical Modeling and Near-Infrared Spectroscopy Monitoring of Vial Lyophilization

    Författare :Mikael Brülls; [2008]
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; in-situ; simulation; monitoring; spectral peak area analysis; near-infrared spectroscopy; lyophilization; moisture; sublimation; vial; mathematical model;

    Sammanfattning : The research documented in this thesis was directed towards lyophilization of pharmaceuticals in vials (vial lyophilization) and it was focused on the design and control of this process. Theoretical modeling has considerable potential to guide experimental studies, thereby decreasing development time and improving the possibilities to achieve an optimal and robust process design. LÄS MER

  2. 2. Control of enzyme activity and stability in nonaqueous media

    Detta är en avhandling från Angeliki Öste Triantafyllou, Dept. of Biotechnology, Lund University, Box 124, 221 00 Lund, Sweden

    Författare :Angeliki Öste Triantafyllou; [1996]
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; polyacrylamide; polar solvent; lyophilization; immobilization; enzymes in nonaqueous media; differential scanning calorimetry; celite; additives; buffers; salts; sorbitol; Biotechnology; Bioteknik;

    Sammanfattning : The use of enzymes in nonaqueous media has considerably expanded their potential areas of application. Limitations however arise that are inherent to the low conformational flexibility of enzymes in dry organic media. Enzyme activity is often unfavorably low due to kinetic barriers. LÄS MER

  3. 3. Advances in exosome-mediated immunotherapy and diagnostics

    Detta är en avhandling från Stockholm : Karolinska Institutet, Dept of Medicine, Solna

    Författare :Pia Larssen; Karolinska Institutet.; Karolinska Institutet.; [2018]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Exosomes are small vesicles with immune-stimulatory capacity, which can activate T cell responses in a B cell dependent manner, and therefore may serve as immune therapeutic tools. Peptide-loaded dendritic cell (DC)-derived exosomes are proven safe in clinical trials, although with limited ability to induce cytotoxic T lymphocyte (CTL) responses or prolong patient survival. LÄS MER

  4. 4. Amine Transaminases in Biocatalytic Amine Synthesis

    Detta är en avhandling från Stockholm : Henrik Land

    Författare :Henrik Land; KTH.; [2016]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Amine Transaminase; Biocatalysis; Transamination; Reductive Amination; Enzyme; Enzyme Engineering; Equilibrium Displacement; Screening; Enzyme Stability; Biotechnology; Bioteknologi;

    Sammanfattning : The use of enzymes, nature´s own catalysts, both isolated or as whole cells to perform chemical transformations is called biocatalysis. As a complement to classical chemical catalysis, biocatalysis can be an environmentally friendly and more economical option in the production and synthesis of chemicals. LÄS MER

  5. 5. Gluten Protein-Based Microcellular Foams and Composites: Development and Functional Properties

    Detta är en avhandling från Stockholm : KTH

    Författare :Thomas Blomfeldt; KTH.; [2010]
    Nyckelord :Wheat Gluten; Foam; Freeze-drying; Glycerol; Bacterial cellulose; Pore structure; Protein structure; Compression; Thermal conductivity; Combustion;

    Sammanfattning : Most common foams are produced from non-renewable resources (e.g., synthetic plastics),with a number of environmental concerns, hence there is a demand for alternative bio-derivedfoam materials. Wheat gluten protein is widely known to have excellent foaming properties(e. LÄS MER