Sökning: "lymphoproliferative malignancies"

Visar resultat 1 - 5 av 12 avhandlingar innehållade orden lymphoproliferative malignancies.

  1. 1. Clinical impact of epoetins in the treatment of anemia with special emphasis on patients with lymphoid malignancies. : dosing, iron supplementation and safety

    Författare :Michael Hedenus; Jack Lindh; Anders Österborg; Robert Hast; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; anemia; cancer; lymphoproliferative malignancies; erythropoietin; intravenous iron; safety; Oncology; Onkologi; Oncology; onkologi;

    Sammanfattning : The aim of this thesis was to determine the relevant dose of arbepoetin-alfa (DA) in patients with lymphoproliferative diseases (LPD) and chemotherapy induced anemia (CIA), to study the clinical impact of intravenous (IV) iron supplementation combined with epoetin beta treatment, to identify factors that might predict hemoglobin (Hb) response to treatment with epoetins and to investigate safety of DA.A dose-finding phase II study was able to assess a reasonable DA dose of 2. LÄS MER

  2. 2. Development of automated fluorescence microscopy methods to assist the diagnosis and treatment of human malignancies

    Författare :Emilie Flaberg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Fluorescence microscopy is a powerful technique used in many biological laboratories. It is often used as an illustrative tool but in combination with manual efforts, valuable quantitative results can also be obtained. LÄS MER

  3. 3. Living and Dying with Primary Sjögren's Syndrome Studies on Aetiology, Treatment, Lymphoma, Survival and Predictors

    Författare :Elke Theander; Internmedicin - epidemiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Skeleton; transplantation; muskelsystem; Skelett; rheumatology locomotion; long-term outcome; Sjögren s Syndrome; Helicobacter pylori infection; prospective cohort studies; SMR; SIR for lymphoproliferative disease; fatigue; health-related quality of life; complement function; oncology; Cytologi; Immunology; cancer; serologi; Immunologi; serology; cancerology; onkologi; reumatologi; muscle system; CD4 T-lymphocytopenia; Cytology;

    Sammanfattning : This work was aimed at improving our understanding of the course of primary Sjögren's syndrome (SS). The Malmö SS patient register and the 2002 American-European Consensus Criteria formed the basis of all studies. Helicobacter pylori (H. LÄS MER

  4. 4. Characterization of non-coding mRNA in Epstein-Barr virus

    Författare :Åsa Isaksson; Göteborgs universitet; []
    Nyckelord :Epstein-Barr virus; EBNA1; IRES; PTLD; alternative splice; nucleotide substitution; protein interactions;

    Sammanfattning : Epstein-Barr virus (EBV) is a human gammaherpesvirus that infects lymphoid and epithelial cells. The virus is the causative agent of infectious mononucleosis, a self-limiting lymphoproliferative disease, and it is additionally associated with various malignancies including Burkitt?s lymphoma, Hodgkin?s disease and lymphoproliferative syndromes in immunocompromised individuals. LÄS MER

  5. 5. The interactome of the Epstein-Barr virus nuclear antigen 5 suggests novel roles in RNA and protein metabolism

    Författare :Josefine Ekholm; Göteborgs universitet; []
    Nyckelord :Epstein-Barr virus; EBNA5; chaperone; proteasome; nucleolus;

    Sammanfattning : Epstein-Barr virus (EBV) is a human herpes virus that infects B and epithelial cells of the oropharynx. EBV is transmitted by saliva and establishes a lifelong latency in over 90% of the world's population. During latency, the virus exists predominantly as multicopy episomes in the nuclei of memory B cells. LÄS MER