Sökning: "lymphocyte subpopulations"

Visar resultat 1 - 5 av 15 avhandlingar innehållade orden lymphocyte subpopulations.

  1. 1. Human T-lymphocyte activation : interactions between lymphocytes and mitogenic or non-mitogenic lectins

    Författare :Marie-Louise Dillner-Centerlind; Stockholms universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP;

    Sammanfattning : The aim of this investigation was to gain further insights in the mechanisms of T-lymphocyte activation by lectins. Interactions between the lectins and purified lymphocytes from human peripheral blood, were studied in the following respects: in vitro culture requirements for lectin induced DNA-synthesis, intercellular regulations of the mitogen response and binding of lectins to lymphocyte surface components. LÄS MER

  2. 2. Factors regulating lymphocyte development and peripheral activation

    Författare :Anna Makowska; Malmö Institutionen för kliniska vetenskaper; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; transplantation; serology; Immunology; NKT cells; TFG beta; Treg; Immunologi; serologi;

    Sammanfattning : Peripheral tolerance is regulated by different types of regulatory T cells, including CD1-restricted T cells and CD4+CD25+ regulatory T (Treg) cells. This thesis has focused on the interactions between T cells and antigen presenting cells (APCs) and the immunregulatory function of TGF-b as two important factors regulating differentiation and activation of T cells in the periphery. LÄS MER

  3. 3. Chronic hepatitis B : immunological, virological and clinical aspects in the natural course and during the combined prednisolone and interferon-alpha-2b therapy

    Författare :Guo-Zhong Fei; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; HBV; IgM and IgG anti-preS2; IgM anti-HBc; CD4 CD8 ratio; lymphocyte subpopulations; HBV DNA; ALT; chronic hepatitis; prednisolone; interferon-alpha;

    Sammanfattning : The aims of this study were to characterize the IgM and IgG antibody responses to well-defined B-cell epitopes within the preS2 region of the HBV envelope proteins in sera from Chinese and Caucasian patients with chronic HBV infection in relation to viral load and liver disease activity. In addition, the effects of the combined prednisolone and interferon- alpha-2b therapy on these parameters, as well as on the peripheral lymphocyte subsets, were studied in Chinese patients with chronic hepatitis B. LÄS MER

  4. 4. Impact of intestinal worms on distal immune response and control of co-infections

    Författare :Xiaogang Feng; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP;

    Sammanfattning : Parasitic worm infections have been suggested to impair control of secondary infections and vaccine efficacy. However, the experimental data regarding the capacity of intestinal nematodes to modulate host immune responses was lacking and the mechanism underlying dampened immune responses, particularly those distal to the gut, incompletely understood. LÄS MER

  5. 5. T Cells and NK Cells in Coronary Artery Disease : Longitudinal and methodological studies in humans

    Författare :Karin Backteman; Jan Ernerudh; Lena Jonasson; Joachim Lundahl; Linköpings universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : Coronary artery disease (CAD) is the leading cause of death worldwide and most often due to atherosclerosis. Atherosclerosis is a chronic inflammatory process that involves the arteries, inclouding those that supply blood to the heart muscle. LÄS MER