Sökning: "lupus"
Visar resultat 1 - 5 av 179 avhandlingar innehållade ordet lupus.
1. Dissecting the Genetic Basis of Systemic Lupus Erythematosus : The Pursuit of Functional Variants
Sammanfattning : Systemic lupus erythematosus (SLE) is a chronic and systemic autoimmune disease that primarily affects women during the childbearing years. SLE is characterized by the production of autoantibodies against nucleic acids and their interacting proteins. LÄS MER
2. Lupus Nephritis – Genetic Impact on Clinical Phenotypes, Disease Severity and Renal Outcome
Sammanfattning : Systemic lupus erythematosus (SLE) is an autoimmune inflammatory disease that can affect every organ system. Lupus nephritis (LN) is one of the more serious SLE manifestations. Whilst the genetic background of SLE has been thoroughly investigated, less is known about the background of LN. LÄS MER
3. Studies on lupus nephritis
Sammanfattning : Systemic Lupus Erythematosus (SLE) is a chronic inflammatory autoimmune disease characterized by multiple organ involvement, production of autoantibodies to nuclear components and local formation or deposition of immune complexes in different organs. Lupus nephritis (LN) is a common and severe manifestation of SLE. LÄS MER
4. Murine Systemic Lupus erythematosus : cellular regulation and molecular mechanisms behind the formation of autoantibodies in autoimmune disease
Sammanfattning : .... LÄS MER
5. Genetic studies on Systemic Lupus Erythematosus : A fine mapping and candidate gene approach
Sammanfattning : Linkage in the 2q37 region was evaluated using microsatellite markers in multi-case families from Sweden, Iceland and Norway. Both the two-point and the multipoint linkage analysis show highly significant LOD scores (Z=4.51 and 6.03, respectively). LÄS MER