Sökning: "lupus anticoagulants"

Hittade 3 avhandlingar innehållade orden lupus anticoagulants.

1. 1. Studies on antibodies against phospholipids

   Författare :Leopold Årfors; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Antiphospholipid syndrome; anticardiolipin antibodies; lupus anticoagulants; platelets; platelet activation; complement activation; endothelial cells; thromboxane; prostacyclin; acetylsalicylic acid.;

   Sammanfattning : The main clinical features of the antiphospholipid syndrome (APLS) are arterial and venous thrombosis, repeated spontaneous abortions and thrombocytopenia. Diagnosed concomitant with an underlying disease the designation is secondary APLS; otherwise primary APLS. LÄS MER

3. 2. Thrombotic and cardiac disease in the antiphospholipid syndrome

   Författare :Giorgia Grosso; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : The antiphospholipid syndrome (APS) is a highly heterogeneous disease that presents with obstetric complications and/or thromboembolic events that can hit any side of the vascular tree in an unpredictable way. The common trait among all patients affected by the syndrome is the persistent presence of the antiphospholipid antibodies (aPL) and/or a prolonged coagulation time in vitro, the lupus anticoagulant (LA) test. LÄS MER

4. 3. Development and evaluation of immunoassays for complement diagnostics

   Författare :Kerstin Sandholm; Kristina Nilsson Ekdahl; Ingvar Ryden; Linnéuniversitetet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immune assays; complement diagnostics; xMAP-technology; C1q; preanalytical factors; method validation; Immunologi; Immunology;

   Sammanfattning : Laboratory analyses of human body fluids play an important role in clinical diagnosis. This thesis comprises projects in which various immune assays have been developed and evaluated as complement diagnostics in both plasma and cerebrospinal fluid (CSF). LÄS MER