Sökning: "lung mechanical model"

Visar resultat 1 - 5 av 59 avhandlingar innehållade orden lung mechanical model.

  1. 1. Intestinal effects of lung recruitment maneuvers

    Författare :Jonas Claesson; Ola Winsö; Stefan Lehtipalo; Conny Arnerlöv; Björn Biber; Göran Hedenstierna; Petter Aadahl; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; acute lung injury; oleic acid lung injury; ischemia; reperfusion injury; swine; mechanical ventilation; lung recruitment; splanchnic circulation; laser Doppler flowmetry; tissue oxygen tension; microdialysis; lactate; glycerol; Anaesthetics and intensive care; Anestesiologi och intensivvård; lungmedicin; Lung Medicine;

    Sammanfattning : Background and aims: Lung recruitment maneuvers (brief episodes of high airway pressure) are a modern treatment alternative to achieve open lung conditions under mechanical ventilation of patients with acute lung injury. It is well known that positive pressure ventilation with high airway pressures cause negative circulatory effects, and that the effects on regional vascular beds can be even more pronounced than the systemic effects. LÄS MER

  3. 2. Transpulmonary pressure during mechanical ventilation

    Författare :Christina Grivans; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mechanical ventilation; Acute lung injury; Acute respiratory distress syndrome; Lung volume measurements; Electric Impedance diagnostic use; Lung elastance; Transpulmonary pressure; Esophageal pressure;

    Sammanfattning : Background: Mechanical ventilation can aggravate lung injury by repetitive opening and closing of lung units, overdistention and undue pressure on pulmonary structures. Guidelines exist for lung protective ventilation, but individualized ventilator settings, based on partitioning of respiratory mechanics in pulmonary and chest wall complex components, would be beneficial. LÄS MER

  4. 3. Open lung concept in high risk anaesthesia : Optimizing mechanical ventilation in morbidly obese patients and during one lung ventilation with capnothorax

    Författare :Henrik Reinius; Filip Fredén; Johan Petersson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Anaesthesia; mechanical ventilation; atelectasis; morbidly obese; one-lung ventilation; PEEP; recruitment maneuver; spirometry; EIT; Anestesiologi och intensivvård; Anaesthesiology and Intensive Care;

    Sammanfattning : Formation of atelectasis, defined as reversible collapse of aerated lung, often occurs after induction of anaesthesia with mechanical ventilation. As a consequence, there is a risk for hypoxemia, altered hemodynamics and impaired respiratory system mechanics. LÄS MER

  5. 4. Pathophysiological and Histomorphological Effects of One-Lung Ventilation in the Porcine Lung

    Författare :Alf Kozian; Göran Hedenstierna; Thomas Hachenberg; Filip Freden; Sten Walther; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alveolar Recruitment Manoeuvre; One-Lung Ventilation; Lung Protective Ventilation; Tidal Volume; Computed Tomography; Tidal Recruitment; Animal Model; Open Thoracic Surgery; Ventilation Perfusion Distribution; Single Photon Emission Computed Tomography; Diffuse Alveolar Damage; Medical laboratory science; Medicinsk laboratorievetenskap; Anestesiologi; Anaesthesiology;

    Sammanfattning : Thoracic surgical procedures require partial or complete airway separation and the opportunity to exclude one lung from ventilation (one-lung ventilation, OLV). OLV is commonly associated with profound pathophysiological changes that may affect the postoperative outcome. LÄS MER

  7. 5. Endothelial function during ischemia-reperfusion and effects of inhalation of nitric oxide

    Författare :Lars Lindberg; Anestesiologi och intensivvård; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; chemiluminescence; capnography; monitoring; inhalation; mechanical ventilation; pulmonary hypertension; nitric oxide; EDRF; endothelium-derived relaxation factor; endothelium; organ preservation; Lung; lung transplantation; electrochemical fuel cell; Anaesthesiology; intensive care; Anestesiologi; intensivvård;

    Sammanfattning : The vascular endothelium is an important regulatory organ in circulatory physiology and plays a central role in the response to acute inflammation and ischemia/reperfusion. Activation and dysfunction of the pulmonary vascular endothelium are closely related to clinical findings of pulmonary dysfunction. LÄS MER