Sökning: "lung inflammation"

Visar resultat 1 - 5 av 238 avhandlingar innehållade orden lung inflammation.

  1. 1. NHBD Lung Transplantation

    Författare :Per Wierup; Thoraxkirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; orthopaedics; traumatology; Kirurgi; ortopedi; traumatologi; Surgery; rat; pig; edema formation; lung preservation; bronchial healing; gas exchange; lung evaluation; Lung transplantation; non-heart-beating donor NHBD ;

    Sammanfattning : The waiting list for lung transplantations world-wide is steadily growing. So, the use of lungs from non-heart-beating donors (NHBD) needs to be addressed. Hence, the aim of this thesis was to evaluate, in realistic animal models, the new donor organ concept: NHBD transplantation. LÄS MER

  3. 2. Cross-modal Imaging in Lung Research: From µCT dosimetry to synchrotron phase contrast microtomography biomechanical insights in preclinical lung injury models

    Författare :Richard Deyhle Jr; Malmö Medicinsk strålningsfysik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Thermoluminescent Dosimetry; Optically stimulated luminescence OSL ; Computed tomography CT ; 4DCT; Phantoms; Imaging; X-rays; pre-clinical models; Pre-clinical; dosimetry: physical basis; biomedical strain; lung injury; mechanical ventilation; inflammation; lung function; synchrotron; histology; acute respiratory distress syndrome ARDS ; Ventilator Inudced Lung Injury VILI ; Histology; Forced Oscillation Technique FOT ; Divergence Theorem; Registration techniques;

    Sammanfattning : Lung diseases continue to present a large burden to public health, especially in industrialized countries. For abetter understanding of the underlying patho-mechanisms in lung related diseases as well as for testing theefficacy of novel therapies, preclinical studies in animal models are indispensable. LÄS MER

  4. 3. Neutrophil and endothelial cell-mediated inflammation in abdominal sepsis

    Författare :Zhiyi Ding; Kirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; sepsis; lung; neutrophil; endothelial cell; neutrophil extracellular traps; inflammation; capillary; post capillary venules; cytoskeleton; RNAseq;

    Sammanfattning : Sepsis is defined as a life-threatening condition caused by a dysregulated host response to infection. Neutrophils are themost abundant innate immune cells of the body and play a key role in septic pathogenesis. LÄS MER

  5. 4. Mechanisms of Lung Injury in a Mouse Model of Bronchopulmonary Dysplasia

    Författare :Anna Hogmalm; Göteborgs universitet; []
    Nyckelord :bronchopulmonary dysplasia; transgenic mice; inflammation; lung; interleukin-1; αvβ6 integrin; mmp-9; surfactant;

    Sammanfattning : Bronchopulmonary dysplasia (BPD) is a chronic lung disease that affects preterm infants. Increased levels of inflammatory mediators in the amniotic fluid and in the lungs of preterm infants are associated with the development of BPD. LÄS MER

  7. 5. Influence of inflammation and of stage of lung development on the development of neonatal lung injury

    Författare :Erica Bäckström; Göteborgs universitet; []
    Nyckelord :premature birth; BPD; inflammation; IL-1β; lung development; gastric aspirates;

    Sammanfattning : Bronchopulmonary dysplasia (BPD) is a major cause of mortality and long-term morbidity in prematurely born infants. Pulmonary inflammation, and abnormal alveolar and vascular development of the lung are histological characteristics of BPD. Interleukin (IL)-1β is a central cytokine in inflammation. LÄS MER