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Visar resultat 1 - 5 av 13 avhandlingar som matchar ovanstående sökkriterier.

  1. 1. Cross-modal Imaging in Lung Research: From µCT dosimetry to synchrotron phase contrast microtomography biomechanical insights in preclinical lung injury models

    Författare :Richard Deyhle Jr; Malmö Medicinsk strålningsfysik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Thermoluminescent Dosimetry; Optically stimulated luminescence OSL ; Computed tomography CT ; 4DCT; Phantoms; Imaging; X-rays; pre-clinical models; Pre-clinical; dosimetry: physical basis; biomedical strain; lung injury; mechanical ventilation; inflammation; lung function; synchrotron; histology; acute respiratory distress syndrome ARDS ; Ventilator Inudced Lung Injury VILI ; Histology; Forced Oscillation Technique FOT ; Divergence Theorem; Registration techniques;

    Sammanfattning : Lung diseases continue to present a large burden to public health, especially in industrialized countries. For abetter understanding of the underlying patho-mechanisms in lung related diseases as well as for testing theefficacy of novel therapies, preclinical studies in animal models are indispensable. LÄS MER

  2. 2. Chronic Obstructive Pulmonary Disease -lung physiology and genetic links

    Författare :Linnea Jarenbäck; allergologi och palliativ medicin Lungmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Chronic obstructive pulmonary disease COPD ; lung physiology; lung function testing; Genetic polymorphism;

    Sammanfattning : .... LÄS MER

  3. 3. Pulmonary atresia with intact ventricular septum epidemiology and outcome in children born in Sweden 1980-1999

    Författare :Britt-Marie Ekman-Joelsson; Göteborgs universitet; []
    Nyckelord :pulmonary atresia with intact ventricular septum; ventriculo coronary arterial communications; biventricular repair; univentricular palliation; myocardial perfusion; myocardial function; cardiopulmonary exercise; lung function; quality of life; mortality; outcome;

    Sammanfattning : Aims: To describe children born with pulmonary atresia with intact ventricular septum (PA-IVS) in Sweden between 1980 and 1999, the incidence and outcome of PA-IVS, to examine cardio-pulmonary outcomes in survivors and to evaluate their quality of life. Material and methods: Eighty-four subjects were identified. LÄS MER

  4. 4. Factors associated with lung function impairment in children and adults with obstructive lung disease

    Författare :Jenny Hallberg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Obstructive lung diseases are a group of diseases in which there is a limitation in the flow of air into or out of the lungs. Two common such diseases are asthma, which is found in both children and adults, and chronic obstructive pulmonary disease (COPD), mainly found in the population over 50 years of age. LÄS MER

  5. 5. Exploring toxicity and fate of metal-based particles in the lung : from mechanistic screening to lung deposition modelling

    Författare :Sarah McCarrick; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : We are all exposed to small particles in the air that we breath and some of them will contain metals in a dose and form that may be harmful. In addition, the field of nanotechnology holds great promises, but an increased production of nanoparticles leads to a higher risk of exposure. LÄS MER