Sökning: "lung function decline"
Visar resultat 21 - 24 av 24 avhandlingar innehållade orden lung function decline.
21. Neutrophil-induced endothelial barrier dysfunction in acute inflammation : mechanisms and therapeutic strategies
Sammanfattning : The acute inflammatory response is characterized by recruitment of leukocytes and increased vascular permeability, resulting in the cardinal signs of inflammation; redness, heat, swelling, pain and loss of function. Permeability changes of the vascular wall are important in functional immune responses and host defense. LÄS MER
22. Adults with cystic fibrosis : mental health and patient experiences of the CF treatment
Sammanfattning : Background: Cystic fibrosis (CF) is an autosomal recessive inherited, life shortening multi organ disease most typically affecting the respiratory system and the gastrointestinal tract. In recent decades progresses in the management of CF has led to an increasing proportion of adults with CF. LÄS MER
23. Studies as a basis for a possible introduction of newborn screening for cystic fibrosis in Sweden
Sammanfattning : Background: Cystic fibrosis (CF) is the most common life-shortening autosomal recessive disease in Caucasians. It is a multi-organ disease that results from mutations in the gene that encodes the CF transmembrane conductance regulator (CFTR) protein, which regulates ion transport at epithelial surfaces. LÄS MER
24. Carcinogenic polycyclic aromatic hydrocarbons : theoretical, molecular, in vitro and cellular characterization of biotransformation and DNA damage
Sammanfattning : Polycyclic aromatic hydrocarbons (PAHs) are widespread mutagenic and carcinogenic environmental pollutants, which require metabolic activation to electrophilic intermediates and subsequent covalent binding to critical targets in DNA to elicit their biological activity. Bayand fjord-region diol epoxides (DEs) have been identified as the ultimate mutagenic and carcinogenic metabolites of PAHs. LÄS MER
