Sökning: "lung function decline"

Visar resultat 16 - 20 av 24 avhandlingar innehållade orden lung function decline.

  1. 16. Fungal colonization and infection in cystic fibrosis : prevalence, consequences and intervention

    Författare :Mahasin Al Shakirchi; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Background: Cystic fibrosis (CF) is an inherited progressive disease affecting multiple organs. The main cause of death in CF is related to the respiratory complications. Inflammation and infection, triggered by colonizing microorganisms in CF airways, cause structural lung damage resulting in respiratory failure and death. LÄS MER

  3. 17. Appeasing the wheezing : determinants and outcomes of respiratory disease in childhood

    Författare :Emma Caffrey Osvald; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The aim of this thesis was to study the determinants and outcomes asthma and cystic fibrosis in childhood by using study populations of persons born in Sweden and data from a clinical cohort and national health and demographic registers and a quality register. In Paper I and Paper II we explored determinants of respiratory disease. LÄS MER

  4. 18. Clinical and genetical studies in cystic fibrosis and pseudohypoaldosteronism

    Författare :Charlotta Schaedel; Lund Pediatrik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pseudohypoaldosteronism type 1; cystic fibrosis transmembrane conductance regulator CFTR ; Cystic fibrosis; pulmonary disorder; Pediatrics; epithelial sodium channel ENaC; Pediatri;

    Sammanfattning : Cystic fibrosis (CF) is the most common severe autosomal recessive disorder among Caucasians and is caused by mutations of the chloride channel, CFTR (cystic fibrosis transmembrane conductance regulator) gene. Despite a markedly improved median survival many CF patients still die at a young age. LÄS MER

  5. 19. Exploring small airways using breath analyses

    Författare :Emilia Viklund; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; exhaled particles; small airways; alveolar nitric oxide; SARS-CoV-2; birch pollen; smoking; lining fluid;

    Sammanfattning : Background: Airway irritants such as allergens, tobacco smoke and viruses may cause damage in the small airways, usually undetected with routine diagnostic methods. Analyses of endogenously produced nitric oxide (NO) and endogenously produced small droplets (i.e. LÄS MER

  7. 20. Obstructive pulmonary disease : Studies of acute exacerbations and immunologic status

    Författare :Inger Dahlén; Uppsala universitet; []
    Nyckelord :Medical sciences; asthma; COPD; acute exacerbations; inflammatory markers; psychologicalfactors; bone markers; immunological skin tests; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Medicine; medicin;

    Sammanfattning : In this thesis, different aspects of the treatment and care of patients with asthma and chronic obstructive pulmonary disease (COPD) have been studied.In a study of 50 patients seeking medical care for an acute exacerbation of asthma or COPD, we studied inflammatory markers in blood, sputum and urine. LÄS MER