Sökning: "luminal matrix"
Visar resultat 1 - 5 av 17 avhandlingar innehållade orden luminal matrix.
1. Molecular regulation of epithelial tube size
Sammanfattning : In nature, epithelial tubes are vital structures in organ design and are required for transport of gases and liquids in organs, such as the vascular system, the vertebrate lung and the kidneys. The tubular epithelium is single layered, but is often reinforced by layers of muscular support. LÄS MER
2. Embryonic ecdysone-induced gene expression and progression of organ morphogenesis
Sammanfattning : The formation of an epithelial organ requires a set of organ-specific gene programs that instruct parallel and successive developmental events. Still, it is unclear what are the core regulatory programs and how such programs are timely coordinated within the organ. LÄS MER
3. Mucin-like proteins in Drosophila development
Sammanfattning : Mucins are large and highly glycosylated proteins and major component of the mucus that coats the lining of epithelial organs. Mucins are characterized by the presence of extended regions rich in the amino acids Proline, Threonine and Serine (PTS domain), where the Serines and Threonines are O-glycosylated to form sugar-rich mucin domains. LÄS MER
4. Matrix degrading proteases in vascular disease
Sammanfattning : Diverse processes of vascular disease including lesion growth, plaque rupture and abdominal aortic aneurysm formation are influenced by protease expression. Arteries undergo compensatory remodelling when the mechanical forces that are imposed on them are altered. LÄS MER
5. New roles for apical secretion and extracellular matrix assembly in Drosophila epithelial morphogenesis
Sammanfattning : Branched tubular organs, such as the lung and vascular system fulfill the respiratory needs of most animals. Optimal tissue function relies on the uniform sizes and shapes of the constituting branches in each organ. LÄS MER
