Sökning: "luminal loop"

Visar resultat 1 - 5 av 7 avhandlingar innehållade orden luminal loop.

  1. 1. Development of a Yeast Model for Functional Analysis of Human Copper Transport Proteins

    Författare :Kumaravel Ponnandai Schanmugavel; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; luminal loop; metal binding domains; Wilson’s disease protein; yeast model; ATP7B; copper transport.;

    Sammanfattning : ABSTRACT Copper (Cu) is an important trace element that plays a vital role in several biological processes. It mediates numerous biochemical functions to maintain cellular homeostasis making it an essential metal for sustaining life. LÄS MER

  3. 2. Development of Computational Methods for Cancer Research: Strategies for closing the feedback loop in omics workflows

    Författare :Ufuk Kirik; Institutionen för immunteknologi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; cancer; proteome profiling; bioinformatics; pathway analysis; mass spectrometry; Quantitative proteomics;

    Sammanfattning : As the ultimate workhorses of the living things, proteins undergo significant regulatory activity throughout the lifetime of a cell or an organism. Many complex diseases effect the protein composition, expression or modification in the cells or tissues they arise in. LÄS MER

  4. 3. Grainy head target genes in epithelial morphogenesis and wound healing

    Författare :Shenqiu Wang; Christos Samakovlis; Paul Martin; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; grh; targets; epidermal wound repair; tracheal tube size control; local immune responses; stit; verm; serp; PGRP-LC; CecA-LacZ; Developmental biology; Utvecklingsbiologi; utvecklingsbiologi; Developmental Biology;

    Sammanfattning : grainy head (grh) genes encode a family of transcription factors conserved from fly to human. Drosophila grh is the founding member of this gene family and has multiple functions, including tracheal tube size control, epidermal barrier formation and reconstruction after wounding. LÄS MER

  5. 4. Retinoid metabolism and signalling in vascular smooth muscle cells

    Författare :Pauline Ocaya; Allan Sirsjö; Andreas C. Gidlöf; William S. Blaner; Örebro universitet; []
    Nyckelord :all-trans Retinol; all-trans Retinoic acid; retinoid metabolism; proliferation; Vascular smooth muscle cells; CYP26; MEDICINE; MEDICIN; Biomedicin; Biomedicine;

    Sammanfattning : Smooth muscle cells (SMCs) play a major role in cardiovascular diseases. In advanced atherosclerosis, blood flow is impaired due to reduced luminal diameter. Percutaneous vascular interventions, including balloon angioplasty and stent-application are commonly used for the re-establishment of luminal size and improvement of tissue perfusion. LÄS MER

  7. 5. Nutritional rehabilitation of persistent diarrhea in childhood : factors determining recovery and the relationship of systemic infections with intestinal function

    Författare :Zulfiqar Ahmed Bhutta; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Persistent diarrhea; Nutritional rehabilitation; Recovery; Infections; Insulin-like growth factor IGF}I; Rat model; Intestinal secretion; Permeability; Cytokines; Nitric Oxide; Motility; Bacteremia.;

    Sammanfattning : Nutritional rehabilitation of persistent diarrhea (PD), a major killer of children in the third world, poses an enormous challenge. We validated the efficacy of a traditional local weaning diet based on rice-lentils (Khitchri) and yogurt (K-Y diet) for nutritional rehabilitation of PD. LÄS MER