Sökning: "low-molecular weight heparin"
Visar resultat 1 - 5 av 29 avhandlingar innehållade orden low-molecular weight heparin.
1. Clinical aspects on treatment of deep venous thrombosis with a low molecular weight heparin
Sammanfattning : Dalteparin is a low molecular weight heparin (LMWH) with a mean mw of 4-6000 D. Compared to unfractionated heparin (UFH), a higher bioavailability, a longer half-life and a more predictable dose-response is achieved after subcutaneous injections. LÄS MER
2. Lipoprotein lipase in hemodialysis patients and healthy controls : effects of heparin
Sammanfattning : Mortality from cardiovascular disease in patients on chronic hemodialysis (HD) is 10 to 20 times greater than in the general population. One major risk factor is renal dyslipidemia, characterised by an impaired catabolism of triglyceride (TG)-rich lipoproteins with accumulation of atherogenic remnant particles. LÄS MER
3. Endothelial and cardiac effects of 5-fluorouracil. An experimental and clinical study
Sammanfattning : The cytostatic drug 5-fluorouracil (5-FU) has been shown to affect both morphology and function of vascular endothelium. These effects could be part of the pathophysiology for 5-FU induced cardiotoxicity. The present thesis explores the mechanisms of this endothelial toxicity. LÄS MER
4. Multi-lead ST-monitoring in the early assessment of patients with suspected or confirmed unstable coronary artery disease
Sammanfattning : This study evaluated the use of multi-lead ST-monitoring in the early assessment of patients with suspected or confirmed unstable coronary artery disease (UCAD).At continuous 12-lead ECG (c12ECG), the definition of an ischemic episode as a transient ST-deviation ¡Ý0 for at least 1 minute resulted in a good observer agreement (kappa=0. LÄS MER
5. Oral anticoagulation and stroke risk
Sammanfattning : Background: The risk of ischaemic stroke in patients with atrial fibrillation (AF) and mechanical heart valve (MHV) prostheses can be reduced by oral anticoagulation (OAC), which increases the risk of serious bleeding. The aims of this thesis were [1] to find out how effective and safe warfarin is where treatment quality is high, i.e. LÄS MER