Sökning: "low molecular weight compounds"

Visar resultat 1 - 5 av 81 avhandlingar innehållade orden low molecular weight compounds.

  1. 1. Ligand binding and enzyme catalysis studied by molecular dynamics simulations

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Tomas Hansson; Uppsala universitet.; [1998]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Molecular biology; molecular dynamics simulation; free energy; linear response; drug design; empirical valence bond; HIV protease; protein tyrosine phosphatase; Molekylärbiologi; NATURAL SCIENCES Biology Cell and molecular biology Molecular biology; NATURVETENSKAP Biologi Cell- och molekylärbiologi Molekylärbiologi; molekylärbiologi; Molecular Biology;

    Sammanfattning : Molecular dynamics simulations and free energy calculations can be applied to biomolecular systems to predict ligand binding affinities. Combined with hybrid quantum-classical potential energy surfaces, such computations can also be used to probe enzymatic catalysis mechanisms. LÄS MER

  2. 2. Towards bacterial valorization of low molecular weight lignin

    Detta är en avhandling från Department of Chemical Engineering, Lund University

    Författare :Krithika Ravi; Lund University.; Lunds universitet.; [2019-10-24]
    Nyckelord :Pseudomonas putida; Microbacterium sp.; Guaiacol; Syringate; Kraft lignin; Bioconversion; Biorefineries;

    Sammanfattning : Lignin is one of the major constituents in lignocellulosic biomass and is the mostabundant source of renewable aromatics on terrestrial ecosystems. The workcarried out in this thesis concerns bacterial conversion of low molecular weightlignin. LÄS MER

  3. 3. Molecular Approaches to Explore Drug-Target Interactions

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Abdullah Al-Amin; Ulf Landegren; Christopher Schofield; [2019]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Drug discovery; target engagement; target engagement-mediated amplification; cellular thermal shift assay; proximity extension assay; in situ PLA; high-content imaging; Molekylär medicin; Molecular Medicine;

    Sammanfattning : Improved means to assess the clinical potential of drug candidates can critically influence development of new therapeutic entities, a central aim in medical life science. Drug discovery and development relies on construction and selection of small organic compounds or biological agents that bind targets of interest. LÄS MER

  4. 4. Selenium Compounds in Milk. Studies of Selenoproteins, Selenium Enrichment and Oxidative Stability of Food

    Detta är en avhandling från Pure and Applied Biochemistry, Lund University

    Författare :Tien Hoac; Lund University.; Lunds universitet.; [2007]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; metabolism; Biokemi; Metabolism; Biochemistry; Naturvetenskap; Natural science; Copper; Zinc; Oxidative stability; Thioredoxin reductase; Glutathione peroxidase; Selenoproteins; Milk; Selenium supplementation; Technological sciences; Teknik;

    Sammanfattning : Selenium is an essential nutrient and in animals and humans it can either be specifically incorporated into proteins as selenocysteine or randomly as selenomethionine. It can also occur as low-molecular-weight compounds and the form of selenium in foods may also influence food quality. LÄS MER

  5. 5. Selenium Compounds and Antioxidant Capacity in Bovine Milk. Studies on Glutathione Peroxidase, Bioavailability and Electrochemical Techniques

    Detta är en avhandling från Pure and Applied Biochemistry, Lund University

    Författare :Jun Chen; Lund University.; Lunds universitet.; [2002]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; General biomedical sciences; Biomedicinska vetenskaper allmänt ; Kemiteknik och kemisk teknologi; Chemical technology and engineering; Livsmedelsteknik; Food and drink technology; amperometry; voltammetry; antioxidant capacity; ileostomy; bioavailability; glutathione peroxidase; bovine milk; selenium;

    Sammanfattning : The efficacy and function of antioxidants have been intensively studied in foods and other biological systems in recent decades. This thesis concerns different aspects of the antioxidant properties of bovine milk, with emphasis on measurement of the total antioxidant capacity (TAC), the activity of the selenium-containing glutathione peroxidase (GSHPx), and the bioavailability of selenium from bovine milk in humans. LÄS MER