Sökning: "low molecular mass heparin"

Visar resultat 1 - 5 av 6 avhandlingar innehållade orden low molecular mass heparin.

1. 1. Unstable coronary artery disease : Studies on inflammation, infection, hemostasis, and the effects of low-molecular-mass heparin treatment

   Författare :Henrik Toss; Uppsala universitet; []
   Nyckelord :Medical sciences; unstable angina; myocardial infarction; prognosis; inflammation; hemostasis; fibrinolysis; resistance to activated protein C. low-molecular-mass heparin; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Medicine; medicin;

   Sammanfattning : The occurrence and prognostic importance, of inflammatory activity, signs of Chlamydia pneumoniae infection. APC resistance, hemostasis, and the effects of low-molecular-mass heparin (LMMH) was evaluated in patients with unstable coronary artery disease (UCAD). LÄS MER

3. 2. Role of Heparan Sulfate N-sulfation in Mouse Embryonic Development

   Författare :Anders Dagälv; Lena Kjellén; Svein Kolset; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; heparan sullfate; heparin; proteoglycan; NDST1; NDST2; coreprotein; syndecan; Biochemistry; Biokemi; Cell biology; Cellbiologi; Biokemi; Biochemistry;

   Sammanfattning : Heparan sulfate (HS) is a sulfated glycosaminoglycan expressed by all cells in the body. It is found at the cell surface and in the extracellular matrix where it binds a large amount of various ligands including growth factors and morphogens. LÄS MER

4. 3. Treatment of deep vein thrombosis and risk of recurrent venous thromboembolism

   Författare :Per Lindmarker; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Deep vein thrombosis; pulmonary embolism; low molecular mass heparin; therapy; outpatients; recurrent; risk factors; APC-resistance; factor V G1691A; prothrombin G20210A; side;

   Sammanfattning : A cute deep vein thrombosis (DVT) and pulmonary embolism (PE) are different clinical presentations of the same underlying disease, namely venous thromboembolism (VTE), which is a common and potentially fatal condition. Risk factors associated with the first and probably also subsequent events of VTE are hereditary or acquired. LÄS MER

5. 4. Diabetic skin microangiopathy : studies on pathogenesis and treatment

   Författare :Majid Kalani; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Diabetes mellitus; chronic foot ulcers; skin microcirculation; peripheral arterial occlusive disease; blood coagulation; fibrinolysis; fibrin gel structure; low molecular weight heparin; dalteparin.;

   Sammanfattning : Background: Most of late diabetic complications have their basis in a disturbed microcirculation, i.e. diabetic microangiopathy. LÄS MER

7. 5. Determination of the overall haemostasis potential and fibrin gel permeability : method development and application in research and in clinical materials

   Författare :Aleksandra Antovic; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Global haemostatic assays; overall haemostasis potential; hypercoagulation; hypocoagulation; thrombophilia; haemophilia; fibrin gel porosity; LMMH therapy; acetylsalicylic acid therapy;

   Sammanfattning : We have previously developed a laboratory method that may screen the Overall Haemostasis Potential (OHP) in plasma based on spectophotometric measurement of an area under the fibrin aggregation curve in citrated plasma samples to which tiny amounts of exogenous thrombin and tissue-plasminogen activator (t-PA) are added. When the fibrin aggregation curve is created, the fibrinogen originally present in plasma is gradually converted to fibrin by the generated thrombin. LÄS MER