Sökning: "losartan"
Visar resultat 1 - 5 av 19 avhandlingar innehållade ordet losartan.
1. Effects of Dehydration and Blockade of the Renin-Angiotensin System in the One-humped Camel (Camelus dromedarius)
Sammanfattning : The one-humped or the dromedarian camel is a pseudo-ruminant mammal, well adapted to the hot and dry climates of the desert. Its ability to withstand torrid heat and extreme desiccation is of paramount importance to its survival. LÄS MER
2. Cytochrome P450 2C9 polymorphism : interindividual differences in drug metabolism and phenotyping methodology
Sammanfattning : Cytochrome P450 2C9 (CYP2C9) is one of the most important drug metabolizing enzymes in human liver. It catalyses the metabolism of a wide range of different drugs such as S-warfarin, acenocoumarol, losartan, irbesartan, phenytoin, sulphamethoxazole, tolbutamide, glipizide and numerous non-steroidal antiinflammatory drugs. LÄS MER
3. Experimental design of phenotyping probe drugs with emphasis on CYP1A2 : their use in studies on genetic and environmental regulation of drug metabolism
Sammanfattning : Assessment of the cytochrome (CYP) P450 enzyme activity or phenotyping is a method to characterise the real activity of an enzyme by the use of a marker probe drug. The information of the phenotype is of clinical relevance because it reflects the combined effects of genetic, environmental e.g. LÄS MER
4. Dopamine coordinates the effect of natriuretic and antinatriuretic factors
Sammanfattning : Living organisms are dependent on a precise regulation of water and sodium. The stability of the internal environment is maintained through a series of feedback mechanisms, in response to changes within the organism as well as to changes in the external environment. LÄS MER
5. The Role of Angiotensin II in Experimental Acute Kidney Injury and Cardiorenal Failure
Sammanfattning : Blood pressure and fluid regulation are kept constant through the interaction between heart and kidneys. When the systemic blood pressure decreases, the levels of the hormone Angiotensin II increase, leading to vasoconstriction and therefore increased blood pressure. LÄS MER