Sökning: "long-term maintenance therapy"
Visar resultat 11 - 15 av 30 avhandlingar innehållade orden long-term maintenance therapy.
11. Stem cell transplantation in multiple myeloma : clinical aspects and experimental gene transfer studies
Sammanfattning : Multiple myeloma (MM) is a hematological malignant disease considered essentially incurable despite its sensitivity to cytotoxic chemotherapeutic drugs and radiation. High-dose chemo/radiotherapy with allogeneic- or autologous hematopoietic stem cell transplantation (tx) can induce a disease-free state and may prolong survival and offer an improved quality of life to MM patients. LÄS MER
12. Epidemiological studies of medication use and effectiveness in bipolar disorder
Sammanfattning : In the last decades, new treatments for bipolar disorder (BD) have emerged, prompting a decrease in the use of lithium – the former “gold standard” for relapse prevention, and increasing the possibilities for individualized treatment. The aims of this thesis were to: 1) explore the use of relapse prevention in the early phases of bipolar illness, 2) add to the current knowledge concerning the comparative effectiveness of various pharmacological maintenance treatments, including combination therapies, and 3) explore the use of benzodiazepines and non-benzodiazepine hypnotics (so called Z-drugs) in BD. LÄS MER
13. On antimicrobial approaches to arrest and control chronic periodontitis
Sammanfattning : The main objectives were to study the effect of frequently repeated supragingival plaque removal on the subgingival microbiota and periodontal pocket reduction and to analyze the adjunctive effect of different antimicrobial agents on the treatment of periodontal disease. Subjects with gingivitis or chronic periodontitis were included. LÄS MER
14. Infections in patients with chronic kidney disease : patterns, outcomes and the role of vitamin D for future prevention
Sammanfattning : Background: Chronic kidney disease (CKD) is increasingly recognized as a global public health problem. Patients with CKD are at high risk of infections. Frequent episodes of infections with greater use of antibiotics might put this population at risk of infections caused by resistant organisms. LÄS MER
15. AB0-incompatible kidney transplantation using antigen-specific immunoadsorption and rituximab
Sammanfattning : 5As the demand for kidney transplantation is constantly growing methods to expand the donor pool have become increasingly important. AB0-incompatibility has hitherto been regarded as an absolute contraindication to living donor donation. LÄS MER