Sökning: "long QT syndrome"
Visar resultat 1 - 5 av 9 avhandlingar innehållade orden long QT syndrome.
1. Long QT syndrome in Sweden : founder effects and associated cardiac phenotypes
Sammanfattning : Background: We aimed to increase the knowledge regarding the familial arrhythmogenic disorder Long QT Syndrome (LQTS) and its recessive variant Jervell and Lange-Nielsen Syndrome (JLNS) in Sweden, including prevalences and clinical phenotypes. A specific focus was directed towards two KCNQ1 mutations –p.Y111C and p. LÄS MER
2. Long QT syndrome : studies of diagnostic methods
Sammanfattning : Background: The Long QT Syndrome (LQTS) is a hereditary heart disease with risk of malignant ventricular arrhythmia and sudden cardiac death. Despite our increased knowledge about genotype and phenotype correlation we still rely on the 12-lead ECG for assessment of the QT interval and the T-wave morphology for diagnosis and risk stratification. LÄS MER
3. Autonomic cardiac control in long QT syndrome : clinical studies of arrhythmogenic triggers
Sammanfattning : Background: Long QT syndrome (LQTS) is an inherited cardiac disease characterized by prolonged cardiac repolarization and an increased risk for life-threatening arrhythmias. These arrhythmias are typically triggered by adrenergic stimuli, such as physical activity and intense emotions, implicating that the sympathetic part of the autonomic nervous system (ANS) is involved in arrhythmogenesis. LÄS MER
4. Myocardial electromechanical function in long QT syndrome
Sammanfattning : AIM: The aim of this thesis is to assess, in LQTS and according to genotype, the myocardial electromechanical (EM) function response to exercise, its relation to symptoms and its response to b-blocker therapy. To achieve this aim, we conducted 4 studies with the following specific objectives: i. LÄS MER
5. Repolarization studies in the long QT syndrome
Sammanfattning : ABSTRACT Background: Sudden cardiac death in the young is predominantly caused by inherited cardiac conditions. Long QT syndrome (LQTS) is one of the most common of these disorders. Since risk stratification relies largely upon the heart rate (HR) corrected QT interval (QTc), it is crucial to identify an appropriate method for QT correction. LÄS MER