Sökning: "localized ectopic expression"

Visar resultat 1 - 5 av 8 avhandlingar innehållade orden localized ectopic expression.

1. 1. Liquid metal microscale deposition for soft and stretchable skin-like electronics : Providing a soft and gentle contact to living beings

   Författare :Bei Wang; Klas Hjort; Zhigang Wu; Magnus Berggren; Uppsala universitet; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; laser patterning; sacrificial mask; liquid metal; strain sensor; skin movement; masking; shrink film; 3D conformal masking; liquid metal particles; soft electronics; stretchable electronics; compliant electronics; skin-like electronics; epidermal electronics; micro-heater; particle sintering; enteroendocrine cells; localized ectopic expression; wettability; flexography printing; conformal transfer printing; hydro printing; plant physiology; drosophila;

   Sammanfattning : Skin-like electronics could provide a soft and gentle contact with living beings for perceiving and delivering the information of pressure, strain, temperature with higher spatial resolution and sensitivity than our skin, without disturbing the user. Gallium-based liquid metal (LM) is an excellent material for soft and stretchable skin-like devices, since it has high electrical and thermal conductivity, flowability, and self-healable capability. LÄS MER

3. 2. An integrative strategy for targeted evaluation of biomarker expression in non-small cell lung cancer

   Författare :Johanna Mattsson; Patrick Micke; Johan Botling; Fredrik Pontén; Åslaug Helland; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; non-small cell lung cancer; prognostic biomarkers; predictive biomarkers; immunohistochemistry; gene expression; COX-2; claudin; ALK; Medicinsk vetenskap; Medical Science;

   Sammanfattning : Despite improvements in therapy, the prognosis for non-small cell lung cancer (NSCLC) patients remains poor, and cure is only possible in localized tumors after surgical resection. A new generation of targeted cancer drugs has led to the expectation that lung cancer therapy can be significantly improved, but these drugs are today only an option in a small subset of NSCLC patients, and their effect is temporary. LÄS MER

4. 3. Human secretoglobins in normal and neoplastic cells and tissues

   Författare :Anna Sjödin; Håkan Hedman; Roger Henriksson; Mårten Fernö; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oncology; secretoglobins; mammaglobin; lipophilin; breast cancer; pituitary; sweat gland; Onkologi; Oncology; Onkologi; onkologi; Oncology;

   Sammanfattning : Secretoglobins is a newly described polypeptide family that has gained a lot of interest in human cancer and inflammation research. Although the first secretoglobin polypeptide was discovered more than 30 years ago, their physiological function is still not known. LÄS MER

5. 4. Regulation of cellular degradation pathways by viral oncoproteins and microRNAs

   Författare :Hao Shi; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : The cellular degradation system actively participates in cell homeostasis. Despite ongoing efforts and much progress in recent years, the underlying mechanisms of these pathways are not entirely understood. LÄS MER

7. 5. Tetrodotoxin-resistant sodium channels in neuropathic pain

   Författare :Jenny Fjell Hjelmström; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :spinal sensory neurons; nociceptor; IB4; tetrodotoxin; sodium channels; SNS PN3; NaN SNS2; gene regulation; NGF; GDNF; in situ hybridization; immunofluorescence; sodium currents; neuropathic pain models; Taiep;

   Sammanfattning : Injury to the peripheral nervous system can cause neuropathic pain. Abnormal sodium channel activity has been implicated as a source of ectopic firing and changes in nociceptive threshold following nerve injury. LÄS MER