Sökning: "local delivery"

Visar resultat 16 - 20 av 198 avhandlingar innehållade orden local delivery.

  1. 16. Organic electronics for precise delivery of neurotransmitters

    Författare :Amanda Jonsson; Magnus Berggren; Daniel Simon; Marco Rolandi; Linköpings universitet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Organic electronic materials, that is, carbon-based compounds that conduct electricity, have emerged as candidates for improving the interface between conventional electronics and biological systems. The softness of these materials matches the elasticity of biological tissue better than conventional electronic conductors, allowing better contact to tissue, and the mixed ionic-electronic conductivity can improve the signal transduction between electronic devices and electrically excitable cells. LÄS MER

  3. 17. Local anaesthesia in term- and preterm infants

    Författare :Marie Anell Olofsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Background: Local anaesthesia is known to be a safe and effective method for postoperative pain manage- ment in adults and children. This convenient method is however rarely used in term and preterm infants, despite its obvious benefits. This is due to lack of research and experience in the area. LÄS MER

  4. 18. Local pharmacological treatment of inner ear disorders

    Författare :Cecilia Engmér Berglin; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Hearing disorders are among the top 10 in terms of burden of disease in middle- and high-income countries, affecting 250 million people worldwide. During the last few decades researchers have made significant advances in understanding the basic mechanisms and molecular biology of inner ear diseases. LÄS MER

  5. 19. Distributed Optimization of P2P Media Delivery Overlays

    Författare :Amir H. Payberah; Seif Haridi; Alberto Montresor; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; P2P overlay networks; P2P live streaming; Distributed optimization; Electronics; Elektronik; Computer and systems science; Data- och systemvetenskap;

    Sammanfattning : Media streaming over the Internet is becoming increasingly popular. Currently, most media is delivered using global content-delivery networks, providing a scalable and robust client-server model. However, content delivery infrastructures are expensive. LÄS MER

  7. 20. Nanoparticle-based drug delivery systems for neural interfaces - a novel approach for improved biocompatibility

    Författare :Alexander Dontsios Holmkvist; Neurofysiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; Neural interfaces; brain damage injury; Minocycline; Gelatin; Nanoparticles; Drug-delivery systems; Biocompatibility; Tissue responses; immunohistochemistry IHC ; Poly D; L-lactic-co-glycolic acid PLGA ; Hydrophobic ion paring; Emulsification-solvent-diffusion method; Drug release; Microglia activation;

    Sammanfattning : The overall purpose of this thesis was to reduce brain tissue responses around implanted microelectrodes using a pharmacological strategy. One of the main aims was to develop and evaluate drug delivery systems that allow local administration of anti-inflammatory pharmaceutics. LÄS MER