Sökning: "local delivery"

Visar resultat 11 - 15 av 198 avhandlingar innehållade orden local delivery.

1. 11. To tear and to heal : pelvic floor dysfunction and childbirth

   Författare :Malin Huber; Katarina Tunón; Pär Nordin; Karin Strigård; Maria Lindqvist; Kjell Å. Salvesen; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pelvic floor disorders; endosonography; dyspareunia; perineum; pain; qualitative research; delivery; Medicine; medicin;

   Sammanfattning : Background: Up to 80% of women are affected by a perineal laceration after their first vaginal birth. An estimated 40–50% of lacerations involve the perineal muscles, and up to 7% are obstetric anal sphincter injuries (OASI). LÄS MER

3. 12. Bioelectronic Devices for Targeted Drug Delivery and Monitoring of Microbial Electrogenesis

   Författare :Arghyamalya Roy; Daniel T Simon; Klas Tybrandt; Christopher Proctor; Linköpings universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Electrophoresis; Extracellular Electron Transfer EET ; Ion Exchange Membranes IEM ; Drug Delivery; Bupivacaine; Chronic Neuropathic Pain; Microfabrication; Inkjet Printing; Organic Electrochemical Transistor OECT ; Fumarate; Shewanella oneidensis; Dorsal Root Ganglia DRG ; Organic Electronic Ion Pump OEIP ;

   Sammanfattning : Despite a range of pain therapies available in the market, 70% of patients report so-called “breakthrough pain”. Coupled with global issues like opioid crisis, there is a clear need for advanced therapies and technologies for pain management. LÄS MER

4. 13. Effects of Microparticulate Drug Delivery Systems : Tissue Responses and Transcellular Transport

   Författare :Eva Ragnarsson; Per Artursson; Lucia Lazorova; David Brayden; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutics; microparticles; vaccine; pDNA vaccine; cationic polymer; gene expression analysis DNA array ; Caco-2; follicle-associated epithelium FAE ; M cell; transcytosis; Yersinia pseudotuberculosis; Galenisk farmaci; Pharmaceutics; Galenisk farmaci;

   Sammanfattning : Over the past decade, the development of macromolecular drugs based on peptides, proteins and nucleic acids has increased the interest in microparticulate drug delivery, i.e., the delivery of drug systems in the nanometer and micrometer ranges. LÄS MER

5. 14. Overcoming Limitations of Iontronic Delivery Devices

   Författare :Maria Seitanidou; Magnus Berggren; Daniel T Simon; Christopher Bettinger; Linköpings universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

   Sammanfattning : Organic electronic devices are considered as one of the best candidates to replace conventional inorganic electronic devices due to their electronic conductive functionality, low-cost production techniques, the ability to tune their optical and electronic properties using organic chemistry, and their mechanical flexibility. Moreover, these systems are ideal for bioelectronic applications due to their softness, biocompatibility, and most importantly, their electronic and ionic transport. LÄS MER

7. 15. Environment-Sensitive Multifunctional Drug Delivery Systems

   Författare :Jian Qin; Mamoun Muhammed; Marcus Textor; KTH; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Materials chemistry; Materialkemi;

   Sammanfattning : Drug delivery systems (DDS) with multiple functionalities such as environment-sensitive drug release mechanisms and visualization agents have motivated the biomedical community as well as materials chemists for more than a decade. This dissertation is concerned with the development of nanoparticles for multifunctional DDS  to tackle several crucial challenges in these complex systems, including polymeric nanospheres which respond to temperature change, superparamagnetic iron oxide nanoparticles/polymeric composite for magnetic resonance imaging contrast agents and drug carriers, immunoresponse of nanomaterials and injectable magnetic field sensitive ferrogels. LÄS MER