Sökning: "lobular carcinoma in situ"

Hittade 2 avhandlingar innehållade orden lobular carcinoma in situ.

  1. 1. Prognosis in carcinoma in situ of the breast

    Författare :Fredrik Wärnberg; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; Breast carcinoma; ductal carcinoma in situ; lobular carcinoma in situ; prognosis; histopathological grade; p53; c-erbB-2; Ki 67; Bcl-2; hormone receptors; angiogenesis; Kirurgi; Surgery; Kirurgi; Surgery; kirurgi;

    Sammanfattning : The incidence of breast cancer is rising steadily in Sweden and the proportion of carcinoma in situ (CIS) has increased appreciably, most likely due to mammography screening. The aim of this study was twofold: (1) to examine risk factors for subsequent invasive breast carcinoma and breast cancer death after primary ductal carcinoma in situ (DCIS) and (2) to study the biology in the progress between in situ and invasive carcinoma. LÄS MER

  3. 2. TISSUE MICROARRAY PERSPECTIVES ON CYCLIN D1 IN BREAST CANCER: Progression, prognosis and prediction

    Författare :Karin Jirström; Tumörmikromiljö; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pathological anatomy; General pathology; tamoxifen resistance; CCND1; Breast cancer; tissue microarrays; Patologi allmän ; patologisk anatomi;

    Sammanfattning : Breast cancer is a truly heterogenous disease, reflected in the existence of a wide spectrum of phenotypic subsets of tumours with varying intrinsic aggressiveness as well as ability to respond to a given treatment. Recent advances in large-scale genomic and proteomic screening techniques have confirmed this heterogeneity also at a molecular level, but there is still a bottleneck to be overcome before the discoveries in the laboratory can be translated into the much more complex clinical situation in order to develop better targeted therapies. LÄS MER