Sökning: "liver"

Visar resultat 21 - 25 av 1132 avhandlingar innehållade ordet liver.

  1. 21. Hepatitis C virus infection. Viral genotypes and factors promoting liver fibrosis

    Författare :Johan Westin; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hepatitis C virus; genotypes; epidemiology; liver fibrosis; histology; scoring; prognosis; alcohol; liver steatosis;

    Sammanfattning : Hepatitis C virus (HCV) is associated with chronic infection in a majority of infected individuals. Chronic hepatitis C may result in liver cirrhosis or hepatocellular cancer and is therefore considered a major health problem worldwide. LÄS MER

  2. 22. Effects of GH and liver-derived IGF-I on growth and metabolism

    Författare :Klara Sjögren; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; GH; IGF-I; Insulin; GHRH; Somatostatin; GHS; Body growth; Body composition; Liver; Bone mineral content; Bone mineral density.;

    Sammanfattning : Growth hormone (GH) exerts major effects on body growth and metabolism. Insulin-like growth factor (IGF) is expressed in response to GH and is known to mediate many of the effects of GH. The largest expression of IGF is found in the liver although it is expressed in virtually every tissue of the body. LÄS MER

  3. 23. Liver Resection for Colorectal Cancer Metastases. Prognostic Factors and Interventions Affecting Outcome

    Författare :LIDEWIJ SPELT; Lund Kirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; artificial neural networks; chemotherapy; colorectal cancer; liver metastasis; liver resection; portal vein embolisation; prognostic factors; survival analysis;

    Sammanfattning : Background: With a yearly incidence of 56 per 100,000 inhabitants, colorectal cancer (CRC) is one of the most common malignancies in the Western world, representing the third leading cause of cancer-related mortality. Within three years after the diagnosis of CRC, 29% of patients will have developed liver metastases. LÄS MER

  4. 24. Mangafodipir trisodium (MnDPDP)-enhanced magnetic resonance imaging of the liver and pancreas

    Författare :Chen Wang; Uppsala universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oncology; Liver; pancreas; neoplasms; metastases; endocrine tumor; MR imaging; contrast medium; mangafodipir trisodium; MnDPDP; manganese; Onkologi; Oncology; Onkologi; diagnostisk radiologi; Diagnostic Radiology;

    Sammanfattning : Contrast-enhanced magnetic resonance imaging (MRI) of the liver and pancreas is frequently performed to improve the sensitivity and specificity of lesion detection in these organs. The concept of using tissue-specific contrast media is to selectively enhance the normal parenchyma, but not lesions, so that the contrast between tumorous and normal tissue is increased, and lesion detectability improved. LÄS MER

  5. 25. PPARs in the regulation of gene expression and lipid metabolism in the liver

    Författare :Ulrika Edvardsson; Göteborgs universitet; Göteborgs universitet; Gothenburg University; Göteborgs universitet; Gothenburg University; []
    Nyckelord :PPARalpha; PPARgamma; PPARgamma2; Wy14; 643; rosiglitazone; liver; hepatocytes; insulin; fatty acids; MTP; ADRP; lipid metabolism; apoB; triglycerides.;

    Sammanfattning : Peroxisome proliferator-activated receptors (PPARs) are ligand-activated transcription factors, regulating genes involved in carbohydrate, lipid and lipoprotein metabolism. Synthetic PPARalpha agonists used in clinic are the fibrates, and their hypotriglyceridemic effect is believed to be the result of decreased VLDL triglyceride secretion and increased turnover of triglyceride-rich lipoprotein particles in the circulation. LÄS MER