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Visar resultat 11 - 15 av 124 avhandlingar som matchar ovanstående sökkriterier.

1. 11. Colorectal Cancer Liver Metastases : Effects of Chemotherapy on Liver Parenchyma and Resections

   Författare :Jozef Urdzik; Agneta Norén; Per Hellman; James O Garden; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

   Sammanfattning : Current multimodal treatment of colorectal cancer liver metastasis often combines liver resections with preoperative chemotherapy with a 5-year survival of 40-50%. Preoperative chemotherapy includes conversion of initially non-resectable situation and control of micrometastatic disease. LÄS MER

3. 12. Stromal collagens in colorectal cancer and in colorectal liver metastases : tumour biological implications and a source for novel tumour markers

   Författare :Hanna Nyström; Malin Sund; Peter Naredi; Per Sandström; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Colorectal cancer; colorectal liver metastases; tumour marker; stroma; type IV collagen; metastatic growth pattern; kirurgi; Surgery;

   Sammanfattning : Background: Colorectal cancer (CRC) remains one of the leading causes of cancer-related mortality. About 50 % of patients with CRC will develop subsequent liver metastases (CLM). The survival for untreated CLM is only a few months and liver resection provides the only chance for a lasting cure. LÄS MER

4. 13. Experimental studies on the effects of hepatocyte-based liver support

   Författare :Helene Lilja; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; Kirurgi; Surgery; Kirurgi; Surgery; kirurgi;

   Sammanfattning : Liver transplantation is limited by lack of donors and consequently there is a need to develop liver support/replacement therapies, such as hepatocyte transplantation (HcTx) and artificial livers. In the present thesis, the effects of these therapies were investigated. First, we established a technique of isolating fetal hepatocytes (FH). LÄS MER

5. 14. Jejunoileal bypass for morbid obesity : studies of the long-term effects

   Författare :Anders Sylvan; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Jejunoileal bypass; Obesity; Surgery; Liver biopsy; Fibrinolytic system; Colonoscopy; Flow cytometry; Cancer risk;

   Sammanfattning : This study was aimed at investigating adverse and beneficial long-term effects of jejunoileal bypass (JIB) sugery in obese patients. The JIB was the first widly used surgical procedure for treatment of morbid obesity. The weight loss was remarkable, but the procedure was declared not appropiate for obesity surgery in the late 1970's. LÄS MER

7. 15. Bleeding Oesophageal Varices. A Clinical Study of Mesocaval Interposition Shunting and Endoscopic Sclerotherapy

   Författare :Björn Isaksson; Malmö Institutionen för kliniska vetenskaper; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; repeated sclerotherapy; mesocaval interposition shunt; lysosomal enzymes; hepatic encephalopathy; bleeding oesophageal varices; Liver cirrhosis; portal hypertension; oesophageal manometry; Surgery; orthopaedics; traumatology; Kirurgi; ortopedi; traumatologi;

   Sammanfattning : This thesis is aimed at evaluating the clinical results of two treatments in patients with bleeding oesophageal varices; the mesocaval interposition shunt (MI shunt) and repeated endoscopic sclerotherapy (ST). 24 patients were randomised to MI shunt and 21 patients to the ST group (mean age 51.6?9.2 and 53. LÄS MER