Sökning: "liver stiffness"
Visar resultat 1 - 5 av 8 avhandlingar innehållade orden liver stiffness.
1. Ultrasound based shear wave elastography of the liver : a non-invasive method for evaluation of liver disease
Sammanfattning : Background: Detecting liver disease at an early stage is important, given that early intervention decreases the risk of developing cirrhosis and subsequently hepatocellular cancer (HCC). The non-invasive ultrasound-based shear wave elastography (SWE) has been used clinically for a decade to assess liver stiffness. LÄS MER
2. Resection of colorectal liver metastases - Impact of preoperative chemotherapy
Sammanfattning : Background Colorectal cancer is a leading cause of cancer related death worldwide. 20-30 % of patients will develop colorectal liver metastases (CRLMs). Surgical resection is the mainstay of treatment for CRLMs, and is often combined with perioperative chemotherapy, which can prolong progression-free survival after resection. LÄS MER
3. From fatty liver to end-stage liver disease through type 2 diabetes
Sammanfattning : The past decades have seen a marked increase in the incidence of type 2 diabetes and nonalcoholic fatty liver disease (NAFLD). Epidemiological studies have clearly demonstrated that there is an association between type 2 diabetes and NAFLD. LÄS MER
4. Impact of Host Genetic Variants on Natural History and Treatment of Hepatitis C Virus Infection
Sammanfattning : Chronic hepatitis C Virus (HCV) infection causes liver disease and may progress to severe fibrosis, cirrhosis, and hepatocellular carcinoma. This thesis aimed to evaluate the impact of host genetics, i.e. LÄS MER
5. Translational Tumor Drug Delivery : Doxorubicin formulation performance, intracellular uptake and molecular diffusion
Sammanfattning : Globally, hepatocellular carcinoma (HCC) is the most common form of liver cancer and a leading cause of cancer death. One important risk factor is liver cirrhosis and the disease progression is characterized by deposition of extracellular matrix proteins that form a fibrous network, which increases liver stiffness and may limit the effectiveness of different treatment strategies. LÄS MER