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Visar resultat 1 - 5 av 26 avhandlingar som matchar ovanstående sökkriterier.

  1. 1. Liver regeneration : With reference to malnutrition and growth factors

    Författare :Stefan Skullman; Linköpings universitet; []
    Nyckelord :cholecystokinin; energy substrates; epidermal growth factor; insulin-like growth factor I; liver composition; liver regeneration; malnutrition; pancreaticobiliary diversion; protein synthesis; rat; transfonning growth factor alpha; MEDICINE; MEDICIN;

    Sammanfattning : The liver has a unique capacity to regenerate after damage, irrespective of cause. The regulatory mechanisms of this regeneration are not fully known. Liver regeneration· is associated with rapid growth and thereby increased demands for energy and synthesis of new compounds. LÄS MER

  3. 2. Liver tissue characterization and influence of chemotherapy in liver surgery

    Författare :Jan Nilsson; Lund Kirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; colorectal liver metastases; liver regeneration; incisional hernia; steatosis; hepatic microcirculation; diffuse reflectance spectroscopy; DRS; sidestream dark-field imaging; SDF; laser speckle contrast imaging; LSCI;

    Sammanfattning : Background & Aims: Primary liver cancer is the second most common cause of death from cancer worldwide. In the western world, the majority of liver malignancies consist of colorectal metastases. Liver resection is the primary treatment for cure in liver tumor disease. LÄS MER

  4. 3. Hormonal regulation of liver and tumor growth

    Författare :Ville Wallenius; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Liver; cytokine; interleukin-6; tumor necrosis factor; primary liver growth promoter; cyproterone acetate; nafenopin; hepatocyte growth factor; HGF receptor; tumor; sarcoma; N-terminal; truncated;

    Sammanfattning : The aims of this thesis were to investigate the regulatory functions of interleukin-6 (IL-6) and tumor necrosis factor-a (TNF-a) on liver growth, and the importance of hepatocyte growth factor (HGF) and the HGF receptor (Met) for growth of mesenchyme-derived tumors. The studies on different types of liver growth, measured as weight, DNA and protein content, and DNA synthesis, were performed on mice lacking the IL-6 or the TNF receptor-1 gene back-crossed to the C57bl/6 strain. LÄS MER

  5. 4. Liver metastases from colorectal cancer. Different strategies and outcomes

    Författare :Valentinus Valdimarsson; Lund Kirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Liver metastases; Colorectal Neoplasms; Hepatectomy; Mortality; Treatment outcome; Retrospective studies; Sweden; Registries; Volume measurements; Repeat hepatectomy; liver surgery; Functional liver volume; Repeated operation; Recurrence;

    Sammanfattning : Patients with colorectal liver metastases (CRLM) increasingly undergo liver resections. The belief is that the resection or ablation of a tumor, when possible, is the only possibility of a cure. LÄS MER

  7. 5. Resection of colorectal liver metastases - Impact of preoperative chemotherapy

    Författare :Sam Eriksson; Lund Kirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Colorectal liver metastases; Preoperative chemotherapy; Liver resection; Hepatic microcirculation; Sarcopenia;

    Sammanfattning : Background Colorectal cancer is a leading cause of cancer related death worldwide. 20-30 % of patients will develop colorectal liver metastases (CRLMs). Surgical resection is the mainstay of treatment for CRLMs, and is often combined with perioperative chemotherapy, which can prolong progression-free survival after resection. LÄS MER