Sökning: "liver function"

Visar resultat 6 - 10 av 340 avhandlingar innehållade orden liver function.

  1. 6. On leukocyte recruitment in endotoxemic liver injury

    Författare :Daniel Klintman; Malmö Institutionen för kliniska vetenskaper; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ortopedi; traumatology; Kirurgi; orthopaedics; Surgery; Sepsis; Liver; Inflammation; Adhesion; Endotoxemia; traumatologi;

    Sammanfattning : Leukocyte recruitment is a key feature of liver injury associated with endotoxemia and systemic inflammation. The aim of this thesis was to define the adhesive mechanisms underlying leukocyte endothelial cell interactions, and the therapeutic potential of interference with specific adhesion molecules in endotoxemic liver damage. LÄS MER

  3. 7. The role of Lhx2 in the hematopoietic stem cell function, liver development and disease

    Författare :Ewa Wandzioch; Leif Carlsson; Stephen A Duncan; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Cell and molecular biology; liver fibrosis; liver development; Lhx2; hematopoietic stem cells; Cell- och molekylärbiologi; Cell and molecular biology; Cell- och molekylärbiologi; molecular cell biology; molekylär cellbiologi;

    Sammanfattning : During embryonic development, generation of functional organs is dependent on proper interactions between different cell types. Elucidation of the mechanisms operating during organ formation might provide insights into the origin of many pathological disorders in the adult. LÄS MER

  4. 8. Rat liver porin : purification, characterization and biogenesis of a channelforming outer mitochondiral membrane protein

    Författare :Monica Lindén; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : The outer mitochondrial membrane has the unique property of being freely permeable to small water soluble substrate molecules. The molecular basis for this biologically important property has been investigated. LÄS MER

  5. 9. Severe and moderate alpha-1-antitrypsin deficiency at the age of 30

    Författare :Elisabeth Bernspång; allergologi och palliativ medicin Lungmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cohort; screening; alpha-1-antitrypsin; lung function; CT densitometry; liver;

    Sammanfattning : Alpha-1-antitrypsin (AAT) is a glycoprotein synthesised in the liver. Its main role is to protect lung tissue from destruction by neutrophil elastase. In severe (PiZZ) AAT deficiency, there is an increased risk of emphysema, especially in smokers. LÄS MER

  7. 10. Human intestinal alkaline phosphatase : tissue expression and serum levels

    Författare :Ulla Domar; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Human alkaline phosphatase; intestinal alkaline phosphatase; blood; blood group; lipid; monoclonal antibody; immunohistochemistry; liver; kidney; pancreas; liver disease; inflammatory bowel disease;

    Sammanfattning : Human alkaline phosphatase (ALP) comprises four isozymes, viz liver/bone/ kidney or tissue unspecific (AP), intestinal (LAP), placental (PLAP) and germ cell or PLAP-like alkaline phosphatase, with their main expression in specific tissues as indicated by their names. The isozymes are coded by different genes, but they are closely related, with more than 50% amino acid sequence homologies. LÄS MER