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Visar resultat 1 - 5 av 340 avhandlingar som matchar ovanstående sökkriterier.

1. 1. Quantitative Evaluation of Contrast Agent Dynamics in Liver MRI

   Författare :Nils Dahlström; Örjan Smedby; Torkel Brismar; Anders Ynnerman; Carsten Thomsen; Linköpings universitet; []
   Nyckelord :Liver; spleen; hepatobiliary system; liver function; MRI; DCE-MRI; Gd-EOBDTPA; Gd-BOPTA; pharmacokinetic; hepatocyte; relaxivity.; MEDICINE; MEDICIN;

   Sammanfattning : The studies presented here evaluate the biliary, parenchymal and vascular enhancement effects of two T1-shortening liver-specific contrast agents, Gd-BOPTA and Gd-EOB-DTPA, in Magnetic Resonance Imaging (MRI) of healthy subjects and of patients.Ten healthy volunteers were examined with both contrast agents in a 1. LÄS MER

3. 2. Renal function after transplantation of the liver and intestine

   Författare :Gustaf Herlenius; Göteborgs universitet; []
   Nyckelord :adult liver transplantation; pediatric liver transplantation; intestinal transplantation; multivisceral transplantation; immunosuppression; calcineurin inhibitors; glomerular filtration rate; renal function; nephrotoxicity; chronic kidney disease; renal replacement therapy; mortality;

   Sammanfattning : Background: Chronic kidney disease (CKD) after liver (LT) or intestinal (IT) transplantation may decrease patient survival. Calcineurin inhibitors (CNI) play a major role in its development. Aims: Describe long term renal function and risk factors for developing CKD in adults and children after LT and IT. LÄS MER

4. 3. The liver in sepsis : a study of liver circulation and some aspects of liver function in experimental peritonitis and in patients with multiple system organ failure

   Författare :Dag Arvidsson; Uppsala universitet; []
   Nyckelord :MEDICINE; MEDICIN;

   Sammanfattning : .... LÄS MER

5. 4. The Non-Invasive Liver Biopsy : Determining Hepatic Function in Diffuse and Focal LiverDisease

   Författare :Mikael Forsgren; Peter Lundberg; Gunnar Cedersund; Bengt Norén; Olof Dahlqvist Leinhard; Steven Sourbron; Linköpings universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY;

   Sammanfattning : The liver is one of the largest organs within the human body and it handles many vital tasks such as nutrient processing, toxin removal, and synthesis of important proteins. The number of people suffering from chronic liver disease is on the rise, likely due to the present ‘western’ lifestyle. LÄS MER

7. 5. Proteomic and Functional Analysis of In Vitro Systems for Studies of Drug Disposition in the Human Small Intestine and Liver

   Författare :Magnus Ölander; Per Artursson; Pär Matsson; Edward L. LeCluyse; Volker Lauschke; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; proteomics; drug disposition; ADMET; drug transport; drug metabolism; hepatotoxicity; small intestine; liver; caco-2; human hepatocytes; cryopreservation; apoptosis; liver zonation; non-parenchymal cells; Farmaceutisk vetenskap; Pharmaceutical Science;

   Sammanfattning : To reach the bloodstream, an orally administered drug must be absorbed through the small intestine and avoid extensive clearance in the liver. Estimating these parameters in vitro is therefore important in drug discovery and development. LÄS MER