Sökning: "liver disease alcohol"
Visar resultat 1 - 5 av 31 avhandlingar innehållade orden liver disease alcohol.
1. Non-Alcoholic Fatty Liver Disease : Insights into Alcohol Consumption, Genetics, and Proteomics
Sammanfattning : NAFLD (Non-Alcoholic Fatty Liver Disease) affects approximately a quarter of the global population and is closely linked to type 2 diabetes mellitus and obesity. The disease spectrum ranges from steatosis and steatohepatitis to fibrosis, cirrhosis, and hepatocellular cancer. LÄS MER
2. Susceptibility to chronic liver disease
Sammanfattning : The onset and the progression of chronic liver disease involve environmental and genetic factors. Hepatic stellate cells (HSCs) are important players in these processes and are the main storage site for retinol. LÄS MER
3. Non-alcoholic fatty liver disease : an emerging liver disease
Sammanfattning : The aim of the study was to evaluate what NAFLD is from a molecular perspective, what influences the disease progression and what the prognosis of the disease is. Fatty liver has earlier often been associated with excessive alcohol intake and only in the last two decades has it been viewed as a condition in non- drinkers i.e. LÄS MER
4. Studies on alcoholic liver disease
Sammanfattning : The overall aim of this thesis was to explore the impact of alcoholic cirrhosis in Sweden, and the relation between drinking patterns and beverage types and alcoholic cirrhosis, and to evaluate the possible role of autoantibodies in the pathogenesis of alcohol related liver disease. We found that rats had appearance of IgG against rat CYP3A 1 and CYP2E 1 during chronic ethanol feeding We found that patients had reactivity against CYP3A4 and CYP2E I in about 20 to 30% and 10 to 20% of the alcoholic sera. LÄS MER
5. Liver cirrhosis-epidemiological and Clinical Aspects
Sammanfattning : Liver cirrhosis is the end-stage of many different chronic liver diseases. Limited data exists on the epidemiology, natural history and complications of liver cirrhosis such as esophageal varices and malignancies in the Nordic countries after the discovery of hepatitis C (HCV). LÄS MER