Sökning: "liver development"

Visar resultat 11 - 15 av 412 avhandlingar innehållade orden liver development.

1. 11. On CXC Chemokines in Endotoxin-Induced Liver Injury

   Författare :Xiang Li; Kirurgi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ortopedi; traumatologi; orthopaedics; traumatology; Kirurgi; Surgery; patologisk anatomi; Patologi allmän ; pathological anatomy; General pathology; intravital microscopy; liver damage; Adhesion; CXC chemokines;

   Sammanfattning : Leukocyte recruitment is a rate-limiting step in endotoxemic liver injury. Leukocyte extravasation is a multistep process, supported by multiple combinations of adhesion molecules and chemokine receptors. This thesis examined the mechanisms of activation, adhesion and extravascular infiltration of leukocytes in endotoxin-induced liver injury. LÄS MER

3. 12. Molecular genetics of B- and T-lymphocyte development

   Författare :Ingela Wikström; Dan Holmberg; Inga-Lill Mårtensson; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; lymphocyte development; Dmu protein; transcription factor; bHLH; E2-2; T cell; B cell; marginal zone; Medical genetics; Medicinsk genetik;

   Sammanfattning : Lymphocytes are essential for the generation of specific immunity. Development of B cells in the bone marrow and T cells in the thymus have several analogous features, and are tightly regulated processes. Even though there is an increasing amount of information concerning lymphopoiesis, a lot of questions remain. LÄS MER

4. 13. The role of MBOAT7 on fatty liver disease

   Författare :Andrea Caddeo; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Liver disease; medicine; Genetics; NAFLD;

   Sammanfattning : Non-alcoholic fatty liver disease (NAFLD) is the main health disorder in internal medicine, affecting one third of the population worldwide. Environmental and genetic factors contribute to NAFLD susceptibility and progression. LÄS MER

5. 14. The Non-Invasive Liver Biopsy : Determining Hepatic Function in Diffuse and Focal LiverDisease

   Författare :Mikael Forsgren; Peter Lundberg; Gunnar Cedersund; Bengt Norén; Olof Dahlqvist Leinhard; Steven Sourbron; Linköpings universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY;

   Sammanfattning : The liver is one of the largest organs within the human body and it handles many vital tasks such as nutrient processing, toxin removal, and synthesis of important proteins. The number of people suffering from chronic liver disease is on the rise, likely due to the present ‘western’ lifestyle. LÄS MER

7. 15. Development and Applications of Microfluidic Devices for Liver-on-a-Chip Studies

   Författare :Philip Dalsbecker; Göteborgs universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Microfluidics; Microphysiological system; Liver-on-a-Chip; Organ-on-a-chip; Hepatocytes; Induced pluripotent stem cells; iPSC; HepG2; LX-2; on-chip differentiation; PDMS; Microfabrication; Shear stress;

   Sammanfattning : Modeling the human physiology in vitro is a challenging task, yet one of importance for the development of drugs and the study of diseases. To better address the complexities of human organs, microfluidic systems called organs-on-chips are being developed to emulate organ-specific environments for cell culture. LÄS MER