Sökning: "liquid biopsy"
Visar resultat 1 - 5 av 8 avhandlingar innehållade orden liquid biopsy.
1. Circulating platelets : a novel liquid biopsy source for cancer diagnostics and therapy stratification
Sammanfattning : As conventional tissue biopsies have several drawbacks, much effort has been directed toward the development of minimal-invasive liquid biopsy platforms for detecting and profiling cancer.Platelets are the second most abundant cells in blood and have very versatile functions both in physiological and pathophysiological conditions. LÄS MER
Sammanfattning : Liquid biopsies are minimally invasive and allow repetitive sampling of body fluids. Analysis of cell-free tumor DNA in liquid biopsies can be used as a biomarker for cancer. However, in most clinically relevant liquid biopsies, cell-free DNA is present at low concentrations, contains minute tumor allele frequencies, and is highly fragmented. LÄS MER
Sammanfattning : Cancer is the common name to a group of biologically diverse malignant neoplastic diseases. Approximately 18 million people are diagnosed with cancer annually and 8.8 million patients die from it. Tumorigenesis and progression of cancer are driven by alterations in the cancer cell genome. LÄS MER
4. Distribution, total number and size of different types of fibres in male and female skeletal muscles : an enzyme histochemical study of whole muscle cross-sections
Sammanfattning : In order to investigate the total number, relative proportions, size variations and distribution patterns of fibres of different types in human skeletal muscles, a technique was developed which allows whole muscle cross-sections to be collected and stained enzyme histochemically. Necropsy material was obtained from m. tibialis anterior and m. LÄS MER
5. Harnessing urinary extracellular vesicles microRNA by acoustic trapping as potential biomarkers for prostate cancer
Sammanfattning : Prostate cancer (PCa) is an interesting study case of clinical management of uncertainty. PCa is the most diagnosed but only the second-leading cause of non-cutaneous cancer-related mortalities among men in developed countries. To put simply, the life-time risk of PCa diagnosis and mortality is approximately 11% and 3% respectively; a ~3. LÄS MER