Sökning: "lipoprotein-associated phospholipase"

Hittade 4 avhandlingar innehållade orden lipoprotein-associated phospholipase.

  1. 1. Lipoprotein-associated phospholipase A2 (Lp-PLA2) Impact and role as cardiovascular risk marker

    Författare :Margaretha Persson; Internmedicin - epidemiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cardiovascular disease; cohort study; epidemiology; Lp-PLA2; PLA2G7 gene; metabolic syndrome; risk factor; stroke;

    Sammanfattning : Lipoprotein-associated phospholipase A2 (Lp-PLA2) is today considered a novel specific vascular inflammatory biomarker. The general aim of this thesis was to study the role and impact of Lp-PLA2 as cardiovascular (CV) risk marker in an epidemiologic perspective. LÄS MER

  2. 2. Carotid stenosis: aspects on progression, stabilization and follow-up

    Författare :Giuseppe Asciutto; Kardiovaskulär forskning - immunitet och ateroskleros; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; atherosclerosis; carotid plaque; echogenity; beta-blockers; inflammation; antibodies anti oxLDL;

    Sammanfattning : Cardiovascular (CV) atherosclerotic diseases are the leading cause of death in Western nations. The presence of a carotid plaque, the degree of carotid stenosis as well as the rate of progression of carotid disease has been shown to be independent predictive factors for future ischemic events. LÄS MER

  3. 3. Low-Density Lipoprotein Oxidation and Renal Dysfunction : New Markers of Poor Prognosis in Patients with Unstable Coronary Artery Disease

    Författare :Nina Johnston; Lars Wallentin; Tomas Jernberg; Agneta Siegbahn; Lena Jonasson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine; myocardial infarction; unstable angina; oxidized low-density lipoprotein; renal function; prognosis; Medicin; Dermatology and venerology; clinical genetics; internal medicine; Dermatologi och venerologi; klinisk genetik; invärtesmedicin;

    Sammanfattning : In patients with unstable coronary artery disease (CAD) biochemical markers are emerging as useful tools in clinical management. In this thesis we studied the use of markers of low-density lipoprotein (LDL) oxidation and renal function. LÄS MER

  4. 4. Detecting the Vulnerable Plaque

    Författare :Andreas Edsfeldt; Kardiovaskulär forskning - immunitet och ateroskleros; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Atherosclerosis; Carotid plaque; Inflammation; Diabetes; LpPLA2; suPAR; Cytokines; Lipids;

    Sammanfattning : Myocardial infarction and stroke, mainly caused by a rupture of an atherosclerotic plaque, are two of the most common causes of mortality and morbidity in the world. Previous studies have pointed out inflammation, driven by inflammatory lipids, as the keystone in the formation of the rupture prone vulnerable plaque. LÄS MER