Sökning: "lipoprotein changes"

Visar resultat 21 - 25 av 60 avhandlingar innehållade orden lipoprotein changes.

  1. 21. Environmental, nutritional and endocrine regulation of metabolic processes in fish

    Författare :Andreas Kullgren; Göteborgs universitet; []
    Nyckelord :lipids; metabolism; temperature; fasting; growth hormone; ghrelin; NMR; metabolomics; Salmo salar; Oncorhynchus mykiss;

    Sammanfattning : Due to seasonal variations in temperature and food availability, fish in temperate regions should be able to make metabolic adjustments to ensure that enough energy is available for the maintenance of basal processes. The major aim of this thesis was to elucidate how the physiology and lipid metabolism of salmonid fish is affected by temperature and food availability, and to clarify aspects of the endocrine control of lipid metabolism. LÄS MER

  3. 22. Retention of atherogenic lipoproteins in atherogenesis

    Författare :Maria Gustafsson; Göteborgs universitet; []
    Nyckelord :apolipoprotein B; atherosclerosis; LDL; LpL; proteoglycans; retention; sPLA2;

    Sammanfattning : Atherosclerosis is the most common cause of death in the industrialized world. The diseaseis characterized by lipid accumulation and inflammation in the arterial wall, which may leadto obstruction of the blood flow. LÄS MER

  4. 23. Hormonal influences on cholesterol and bile acid metabolism : focusing on involvement of PCSK9

    Författare :Moumita Ghosh Laskar; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Elevated plasma LDL-C is today considered a causative factor for the development of atherosclerosis. Increased plasma LDL-C levels are mainly due to reduced numbers of functional LDL receptors (LDLRs) in the liver. LÄS MER

  5. 24. Functional study of nuclear receptors and bile acids in the modulation of cholesterol homeostasis

    Författare :Xiaoli Hu; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Cholesterol carries multiple biological functions in the body, and imbalanced cholesterol metabolism leads to atherosclerosis and cardiovascular diseases. The present thesis aims to extend the knowledge of cholesterol metabolic regulation mediated by nuclear receptor LXRs and bile acids, two major players in the homeostasis of body cholesterol. LÄS MER

  7. 25. Fighting cardiometabolic disease : validation of new experimental models and therapeutic targets

    Författare :Mirko Enea Minniti; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The prevalence of cardiometabolic diseases (CMD) such as atherosclerotic cardiovascular diseases, type 2 diabetes mellitus and nonalcoholic fatty liver disease (NAFLD), has grown dramatically during the last decades. Hence, massive research efforts are allocated to identify the pathophysiological mechanisms and new therapeutic targets for these morbidities. LÄS MER