Sökning: "lipolysis"

Visar resultat 21 - 25 av 105 avhandlingar innehållade ordet lipolysis.

1. 21. Studies on the regulation of human skeletal muscle lipolysis in vivo

   Författare :Veronica Quisth; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Intramuscular triglycerides; skeletal muscle; lipolysis; insulin; catecholamines; microdialysis;

   Sammanfattning : Intramuscular triglyceride deposits are a significant energy source, and are considered to be of importance in the pathogenesis of skeletal muscle insulin resistance. In contrast to adipose tissue, the lipolytic process in skeletal muscle is not well characterised. LÄS MER

3. 22. Polycystic ovary syndrome : a study of adipocyte lipolysis in relation to endocrine and metabolic status

   Författare :Ingvar Ek; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Adipocyte; beta-adrenoceptors; FFA; hyperandrogenism; HSL; insulin resistance; lipolysis; PCOS; PKA;

   Sammanfattning : The aim of the present thesis was to obtain insight into possible regulatory effects of androgens on the regulation of lipolysis in subcutaneous as well as visceral adipose tissue in women with the polycystic ovary syndrome (PCOS). In non-obese women with PCOS, adrenergic lipolysis was investigated in both subcutaneous abdominal and visceral adipose tissue and several, novel disturbances were found. LÄS MER

4. 23. Insulin Signalling in Human Adipocytes and its Interplay with beta-Adrenergic Control of Lipolysis

   Författare :Cecilia Karlsson; Peter Strålfors; Maria V Turkina; Jan Eriksson; Linköpings universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

   Sammanfattning : The prevalence of obesity has over the last 40 years nearly tripled and obesity is one of the major risk factors of developing type 2 diabetes. Type 2 diabetes was formerly called adultonset diabetes but today, probably due to the rise in childhood obesity, it is also seen in children and adolescents. LÄS MER

5. 24. Applications of microdialysis in studies of the adrenergic regulation of lipolysis in human skeletal muscle and adipose tissue

   Författare :Staffan Enoksson; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Human; in vivo; microdialysis; ethanol technique; lipolysis; blood flow; microcirculation; skeletal muscle; adipose tissue; adrenoceptors; insulin; forskolin; adenylyl cyclase; phosphodiesterases; glycerol; lactate.;

   Sammanfattning : Lipolysis, i.e., hydrolysis of triaeylglycerol to free fatty acids and glycerol, is a central process in lipid metabolism, and the regulation of lipid metabolism is altered in several common disorders, such as diabetes, obesity and atherosclerosis. LÄS MER

7. 25. Hormonal regulation of phosphodiesterase 3B in adipocytes

   Författare :Rebecka Lindh; Signaltransduktionsforskning; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; secreting systems; diabetology; Endokrinologi; Endocrinology; caveolae localization ; phosphorylation interactions ; PDE3B adipocyte adipose tissue diabetes cAMP insulin ; lipolysis caveolin-1 ; sekretion; diabetologi;

   Sammanfattning : Insulin induced activation of the cAMP degrading enzyme phosphodiesterase (PDE) 3B in adipocytes is important for insulin mediated inhibition of lipolysis. The aim of this thesis was to contribute with knowledge on the acute activation of PDE3B in response to insulin and catecholamines in adipocytes. LÄS MER