Sökning: "lipolysis"

Visar resultat 11 - 15 av 106 avhandlingar innehållade ordet lipolysis.

1. 11. Cyclic Nucleotide Phosphodiesterase 3B: Regulation in rat adipocytes and 3T3-L1 cells

   Författare :Tova Landström; Institutionen för experimentell medicinsk vetenskap; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; 3T3-L1 TNF-alpha; adipocyte; insulin; p70S6 kinase; mitogen-activated protein kinase; protein kinase B; phosphatidylinositol-3 kinase; phosphodiesterase 3B; cAMP; lipolysis; phosphorylation; signal transduction; Biochemistry; Metabolism; Biokemi; metabolism;

   Sammanfattning : Insulin stimulation of rat adipocytes results in phosphorylation and activation of the cyclic nucleotide phosphodiesterase 3B (PDE3B), a key enzyme in the antilipolytic signalling pathway of this hormone. In this thesis, the site phosphorylated in PDE3B upon stimulation of rat adipocytes with insulin and/or the beta-adrenergic agonist, isoproterenol is identified. LÄS MER

3. 12. AMP-activated protein kinase in adipose tissue

   Författare :Franziska Kopietz; Institutionen för experimentell medicinsk vetenskap; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; AMPK; adipose tissue; adipocytes; diabetes; insulin; glucose uptake; lipolysis; FA synthesis; ADaM site activators;

   Sammanfattning : The AMP-activated protein kinase (AMPK) is a ubiquitously expressed kinase, which is activated in response to depletion of cellularenergy levels. Once active, it functions to alter cellular metabolism in a way that leads to restoration of energy levels. Therefore,AMPK is described as the key regulator of cellular energy homeostasis. LÄS MER

4. 13. Adverse drug effects on glucose and lipid metabolism: is human adipose tissue of importance?

   Författare :Assel Sarsenbayeva; Jan Eriksson; Mikael Rydén; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; human adipose tissue; metabolic adverse effects; SGAs; statins; glucocorticoids; glucose uptake; lipolysis; myofibroblasts; fibrosis; Endocrinology and Diabetology; Endokrinologi och Diabetologi;

   Sammanfattning : Many pharmacological agents that are widely prescribed in clinical practice have adverse metabolic effects, such as hyperglycaemia, insulin resistance, and diabetes. Among such drugs are antipsychotics, prescribed for treatment of schizophrenia; statins, which inhibit cholesterol synthesis and prevent cardiovascular events; finally, potent anti-inflammatory agents, glucocorticoids. LÄS MER

5. 14. Short-Chain Fatty Acid Starch Stabilized Pickering Emulsions : Design, Properties and Applications

   Författare :Nabilah Binti Abdul Hadi; Avdelningen för livsmedel och läkemedel; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Short-chain fatty acid starch; Physicochemical properties; Pickering emulsions; Starch modification; Emulsion stability; Starch hydrolysis; In vitro digestion; Lipolysis;

   Sammanfattning : Pickering emulsions are emulsions stabilized by solid particles. Particles with optimal dual wettability toward both of the oil and water phases, can be adsorbed onto the interface, thereby providing the stability of the emulsions. LÄS MER

7. 15. Role of nuclear receptors in the regulation of human adipose tissue metabolism

   Författare :Prasad G. Kamble; Jan W Eriksson; Ingrid Dahlman; Uppsala universitet; []
   Nyckelord :human adipose tissue; nuclear receptors; glucocorticoids; estrogen; PPARγ; lipocalin 2; glucose uptake; lipolysis; adipogenesis; genotype-based recall;

   Sammanfattning : Nuclear receptors modulate expression of genes involved in adipose tissue (AT) metabolism. Their improved understanding may provide new treatment options for metabolic disorders such as obesity, insulin resistance (IR) and type 2 diabetes (T2D). LÄS MER