Sökning: "lipid-lowering drugs"

Visar resultat 21 - 25 av 26 avhandlingar innehållade orden lipid-lowering drugs.

1. 21. Atherosclerosis and Insulin Resistance AIR A cross-sectional study of 58-year old men

   Författare :Lena Bokemark; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Insulin resistance; intima-media thickness; LDL particle size; atherosclerosis.;

   Sammanfattning : The main aim of the study was to test the hypothesis that insulin resistance is associated with atherosclerotic disease in the carotid and femoral arteries as measured using the ultrasound technique in clinically healthy 58-year old men with varying degrees of obesity and insulin resistance. The subjects were recruited from the general population and were free from clinical cardiovascular disease, diabetes mellitus and treatment with antihypertensive, lipid-lowering and anti-diabetic drugs (n=818). LÄS MER

3. 22. Coffee and gene interaction. The effect on methionine and lipid metabolism

   Författare :Elisabeth Strandhagen; Göteborgs universitet; []
   Nyckelord :coffee; homocysteine; cholesterol; folate; pyridoxine; MTHFR; APOE; gene; polymorphism; interaction;

   Sammanfattning : Background: Different dietary factors influence the risk of coronary heart disease (CHD), most likely in an interaction with genetic polymorphisms. The knowledge about such interactions is insufficient. Some observational studies have shown an association between coffee and CHD, others have not. Coffee consumption affects some CHD risk factors, e. LÄS MER

4. 23. Understanding therapeutic traditions in a multilevel framework - new methodological approaches

   Författare :Henrik Ohlsson; Malmö Institutionen för kliniska vetenskaper; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; adherence to guidelines; practice variation; Multilevel models; variance components; determinants of prescription;

   Sammanfattning : Background: The observation of differences in the way apparently similar patients are treated from one health care setting to another, i.e., practice variation, have been recognized in numerous studies. The variations across the health care settings have been shown to exist for different outcomes. LÄS MER

5. 24. Hyperlipidaemia : an evaluation of management and attitudes among doctors and knowledge and attitudes in the population

   Författare :Birgitta Danielsson; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :hyperlipidemia; attitude of health personnel; attitude to health; physicians; general practice; occupational health services; internal medicine; risk factors; coronary disease; patient care management; medical decision making; guidelines;

   Sammanfattning : An evaluation of management and attitudes among doctors and knowledge and attitudes in the population Coronary heart disease (CHD) is the main cause of death in the western world, and hyperlipidaemia is one of the major risk factors. Lipids have been the focus of much discussion among both doctors and the public. LÄS MER

7. 25. Native protein mass spectrometry of nuclear receptor-ligand and enzyme-substrate complexes

   Författare :Johan Lengqvist; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Mass spectrometry; electrospray; nuclear receptor; retinoid X receptor; fatty acid; membrane protein; glutathione transferase; glutathione;

   Sammanfattning : Nuclear receptors (NRs) are transcription factors that are activated by the binding of low molecular weight ligands. The NR superfamily includes receptors for steroid hormones, anti-inflammatory and lipid-lowering drugs as well as endogenous compounds such as bile acids and fatty acids. LÄS MER