Sökning: "lipid-lowering drugs"

Visar resultat 11 - 15 av 26 avhandlingar innehållade orden lipid-lowering drugs.

  1. 11. Studies of pancreatic islet microcirculation and insulin secretion in normal and diabetic rats

    Författare :Zhen Huang; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :diabetes; islet; insulin; microcirculation; ethanol; blood flow; hypoglycemia; renin angiotensin system; statins;

    Sammanfattning : Type 2 diabetes is increasing globally. The disease is characterized not only by hyperglycemia, but also by insulin resistance with attendant dyslipidemia, hypertension and endothelial dysfunction. These aberrations may result in macrovascular disease, and deeply impact the longevity and quality of life in diabetic patients. LÄS MER

  3. 12. Epidemiological studies on socioeconomic inequalities and cardiovascular disease : prevention, progression and prognosis

    Författare :Ninoa Malki; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Cardiovascular disease (CVD) accounts for 30% of global mortality and is the most common cause of death in the world. Population-wide prevention strategies as well as healthcare interventions have led to a decrease in CVD incidence and mortality. LÄS MER

  4. 13. Evaluation of risk factor modification management in patients with coronary heart disease and patients´ experiences of secondary prevention

    Författare :Mona From Attebring; Göteborgs universitet; []
    Nyckelord :Coronary heart disease; myocardial infarction; secondary prevention; risk factor modification; smoking cessation; validation; predictors; patients experiences; nursing;

    Sammanfattning : Aim: To evaluate management of risk factor modification among patients suffering from coronary heart disease and to explore patients experiences of secondary prevention. Methods: After establishing a secondary prevention programme, patients were offered follow-up visits to a nurse, one year after the coronary event for evaluation of various risk factors associated with recurrence (I, II). LÄS MER

  5. 14. Energy metabolism and angiogenesis in atherosclerosis and cancer

    Författare :Matias Ekstrand; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Energy metabolism; Hypoxia; Reactive oxygen species; Intussusceptive angiogenesis;

    Sammanfattning : Energy metabolism requires supply of glucose and oxygen. In atherosclerotic plaques and cancer tumors, there are local areas with mismatch in demand and supply of oxygen and nutrients. The resulting cellular energy imbalance may promote energy failure and stimulation of angiogenesis. LÄS MER

  7. 15. Cardioprotective mechanisms by inhibition of the HMG-CoA reductase pathway and stimulation of peroxisome proliferator-activated receptors in myocardial ischaemia-reperfusion

    Författare :Aliaksandr Bulhak; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Endothelial function; endothelin-1; geranylgeranyl pyrophosphate; HMG-CoA reductase; infarct size; ischaemiareperfusion injury; myeloperoxidase; myocardium; nitric oxide; nitric oxide synthase; peroxisome proliferator-activated receptor-alpha; -gamma; PPAR-alpha; -gamma-ligands; RhoA; statins.;

    Sammanfattning : Acute myocardial ischaemia causes metabolic changes and results in a rapid decrease in the energy available to the cell. This leads to cell injury that, depending on the length of the ischaemic time, is reversible or irreversible. LÄS MER