Sökning: "lipid vesicles"

Visar resultat 16 - 20 av 145 avhandlingar innehållade orden lipid vesicles.

  1. 16. Physical characterization of exosomes and other extracellular vesicles using surface-based sensing

    Författare :Deborah Rupert; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; nanoparticle tracking analysis; exosomes; scattering; surface-based biosensing; optical density; cluster of differentiation 63 CD63 ; liposomes; label-free; fluorescence; surface plasmon resonance; Extracellular vesicles; specificity; antibody; lipid content; single particle; quantification; size distribution; optical waveguide microscopy;

    Sammanfattning : Extracellular vesicles (EVs) are hundred of nanometer sized particles secreted by almost all cell types. Exosomes are one type of EVs today intensively investigated due to the increased evidence suggesting that they play important roles as communicating vehicles in a broad range of physiological processes, pathological conditions and disease diagnostics. LÄS MER

  2. 17. Lipid Nanotube Networks: Shape Transitions and Insights into the Dynamics of Self-Organization

    Författare :Tatsiana Lobovkina; Chalmers tekniska högskola; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; circular nanotube; shape transition; enzymatic reaction; nanotube knot; self-organization; liposome; lipid nanotube; lipid vesicle; nanotube-vesicle network;

    Sammanfattning : Nanotube-vesicle networks (NVNs) are simplified models of cell membrane tubular systems which are dynamic transportation routs for molecular cargoes in biological cells. The presented work describes dynamic properties of NVNs such as self-organization, shape and topology transformations; moreover, specific geometric properties of the networks are used for controlling enzymatic reactions. LÄS MER

  3. 18. QCM-D with focus on variations in oscillation amplitude

    Författare :Malin Edvardsson; Chalmers tekniska högskola; []
    Nyckelord :shear oscillation; actuator; Quartz crystal microbalance; amplitude; streptavidin; lipid vesicles; biosensor; colloidal particles; size distribution; QCM-D; protein binding; DNA hybridization; dual harmonic; lipid bilayer formation;

    Sammanfattning : The QCM-D (quartz crystal microbalance with dissipation monitoring) technique is an increasingly popular tool in studies of molecular interactions at interfaces, e.g. binding/unbinding reactions at surfaces, studies of thin film properties, and conformational changes. LÄS MER

  4. 19. Formation of Mesoporous Materials and their use as Lipid Bilayer Supports

    Författare :Maria Wallin; Chalmers tekniska högskola; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; tethered lipid bilayers; meso-ordered PEG-DA hydrogels; dendrimers; porous silica and titania; lipid bilayers; biosensing;

    Sammanfattning : Mesoporous materials have acquired great scientific interest in various applications; something that is largely due to that their properties, such as pore size, pore orientation, material composition and surface chemistry, can be controlled to a large extent. One idea, which has been investigated in this thesis, is to use mesoporous materials as supports for lipid bilayers and by doing so fabricate devices that mimic the cell wall and at the same time has sufficient mechanical robustness for practical use. LÄS MER

  5. 20. Isolation Strategies and Proteomic Characterization of Extracellular Vesicles

    Författare :Aleksander Cvjetkovic; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Extracellular vesicles; Exosomes; Colorectal cancer; Proteomics;

    Sammanfattning : “Extracellular vesicles” is the collective term used to describe vesicular entities that are released from cells into the extracellular environment. These vesicles are composed of a delineating lipid membrane and its cargo which can comprise of bioactive molecules such as lipids, RNA, DNA and proteins which can be shuttled between cells and thus function as a means of cell-to-cell communication. LÄS MER